Evidence map›Paper›PMID 36362369›Full record

ReviewInternational journal of molecular sciences2022

Circulating Tumor Cells in Colorectal Cancer: Detection Systems and Clinical Utility.

József Petrik, Donatella Verbanac, Marija Fabijanec, Andrea Hulina-Tomašković, Andrea Čeri, Anita Somborac-Bačura, Roberta Petlevski, Marija Grdić Rajković, Lada Rumora, Božo Krušlin and 8 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

József PetrikDepartment of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000 Zagreb, Croatia.ORCID 0000-0002-9395-4852
Donatella VerbanacDepartment of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000 Zagreb, Croatia.ORCID 0000-0002-9106-1604
Marija FabijanecDepartment of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000 Zagreb, Croatia.
Andrea Hulina-TomaškovićDepartment of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000 Zagreb, Croatia.
Andrea ČeriDepartment of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000 Zagreb, Croatia.
Anita Somborac-BačuraDepartment of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000 Zagreb, Croatia.ORCID 0000-0002-8573-4294
Roberta PetlevskiDepartment of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000 Zagreb, Croatia.
Marija Grdić RajkovićDepartment of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000 Zagreb, Croatia.
Lada RumoraDepartment of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000 Zagreb, Croatia.
Božo KrušlinSchool of Medicine, University of Zagreb, Šalata 3, 10000 Zagreb, Croatia.
Mario ŠtefanovićDepartment of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000 Zagreb, Croatia.ORCID 0000-0002-3965-3231
Neven LjubičićSchool of Medicine, University of Zagreb, Šalata 3, 10000 Zagreb, Croatia.
Neven BaršićSchool of Medicine, University of Zagreb, Šalata 3, 10000 Zagreb, Croatia.
Antonija HanžekUPR CHROME, University of Nimes, 7 Place Gabriel Peri, 30000 Nîmes, France.ORCID 0000-0003-0143-1470
Luka BočkorCentre for Applied Bioanthropology, Institute for Anthropological Research, Ljudevita Gaja 32, 10000 Zagreb, Croatia.ORCID 0000-0002-2096-0944
Ivana ĆelapDepartment of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000 Zagreb, Croatia.ORCID 0000-0002-3982-5777
Alma DemirovićDepartment of Pathology and Cytology "Ljudevit Jurak", University Hospital Centre "Sestre milosrdnice", University of Zagreb, Vinogradska 29, 10000 Zagreb, Croatia.
Karmela BarišićDepartment of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Ante Kovačića 1, 10000 Zagreb, Croatia.
University of Zagreb · HRUniversity Hospital Centre Zagreb · HRInstitute for Anthropological Research · HRUniversité de Nîmes · FR

Funding

Croatian Science Foundation HRZZ IP-2019-04-4624
6 · The paper itself

Abstract

Colorectal cancer (CRC) is the third most common cancer worldwide. The high mortality from CRC is mainly related to metastasis affecting distant organs and their function. Dissemination of tumor cells from the primary tumor and hematogeneous spread are considered crucial in the formation of tumor metastases. The analysis of circulating tumor cells (CTCs) and CTC clusters in the blood can be used for the early detection of invasive cancer. Moreover, CTCs have a prognostic significance in the monitoring of a malignant disease or the response to chemotherapy. This work presents an overview of the research conducted on CTCs with the aim of finding suitable detection systems and assessing the possibility of clinical applications in patients with CRC.

Indexed as

Colorectal NeoplasmsNeoplastic Cells, CirculatingBiomarkers, TumorCell CountHumansBiomarkers, Tumorcirculating tumor cellsclinical utilitycolorectal cancerCTC clustersdetection methodsisolation techniquesliquid biopsyviable CTCs

Identifiers

PMID36362369
PMCPMC9654465
OpenAlexW4308522286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.