Evidence map›Paper›PMID 36362366›Full record

ReviewInternational journal of molecular sciences2022

The Polyvalent Role of NF90 in RNA Biology.

Giuseppa Grasso, Rosemary Kiernan

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Beyond transcription: RNA-binding proteins steering angiogenesis.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Giuseppa GrassoUMR9002 CNRS-UM, Institut de Génétique Humaine-Université de Montpellier, Gene Regulation Lab, 34396 Montpellier, France.
Rosemary KiernanUMR9002 CNRS-UM, Institut de Génétique Humaine-Université de Montpellier, Gene Regulation Lab, 34396 Montpellier, France.ORCID 0000-0001-6645-0686
Centre National de la Recherche Scientifique · FR

Funding

European Research Council RNAmedTGSFondation ARC pour la Recherche sur le Cancer ARCDOC42020010001205MSD Avenir Hide, Inflame&Seq
6 · The paper itself

Abstract

Double-stranded RNA-binding proteins (dsRBPs) are major players in the regulation of gene expression patterns. Among them, Nuclear Factor 90 (NF90) has a plethora of well-known functions in viral infection, transcription, and translation as well as RNA stability and degradation. In addition, NF90 has been identified as a regulator of microRNA (miRNA) maturation by competing with Microprocessor for the binding of pri-miRNAs in the nucleus. NF90 was recently shown to control the biogenesis of a subset of human miRNAs, which ultimately influences, not only the abundance, but also the expression of the host gene and the fate of the mRNA target repertoire. Moreover, recent evidence suggests that NF90 is also involved in RNA-Induced Silencing Complex (RISC)-mediated silencing by binding to target mRNAs and controlling their translation and degradation. Here, we review the many, and growing, functions of NF90 in RNA biology, with a focus on the miRNA pathway and RISC-mediated gene silencing.

Indexed as

MicroRNAsNuclear Factor 90 ProteinsBiologyHumansRNA, MessengerRNA StabilityMicroRNAsNuclear Factor 90 ProteinsRNA, MessengerdsRBPgene regulationmiRNANF90posttranscriptional regulationRISC

Identifiers

PMID36362366
PMCPMC9655348
OpenAlexW4308568128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.