Evidence map›Paper›PMID 36362345›Full record

ReviewInternational journal of molecular sciences2022

Natural Products for Esophageal Cancer Therapy: From Traditional Medicine to Modern Drug Discovery.

Jeongeun An, Soojin An, Min Choi, Ji Hoon Jung, Bonglee Kim

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jeongeun AnCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Soojin AnCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Min ChoiCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Ji Hoon JungCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0002-5644-5960
Bonglee KimCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0002-8678-156X
Kyung Hee University · KR

Funding

a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea HF20C0038a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea HF20C0116Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education NRF-2020R1I1A2066868NIEHS NIH HHS 27302C0038the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) No. 2020R1A5A2019413
6 · The paper itself

Abstract

Esophageal cancer (EC) is one of the most malignant types of cancer worldwide and has a high incidence and mortality rate in Asian countries. When it comes to treating EC, although primary methods such as chemotherapy and surgery exist, the prognosis remains poor. The purpose of this current research is to review the range of effects that natural products have on cancer by analyzing studies conducted on EC. Fifty-seven studies were categorized into four anti-cancer mechanisms, as well as clinical trials. The studies that were scrutinized in this research were all reported within five years. The majority of the substances reviewed induced apoptosis in EC, acting on a variety of mechanisms. Taken together, this study supports the fact that natural products have the potential to act as a candidate for treating EC.

Indexed as

Biological ProductsEsophageal NeoplasmsDrug DiscoveryHumansIncidenceMedicine, TraditionalBiological Productsangiogenesisapoptosisesophageal cancerherbal medicinemetastasisnatural productresistancetraditional medicine

Identifiers

PMID36362345
PMCPMC9657766
OpenAlexW4308524281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.