Evidence map›Paper›PMID 36362344›Full record

ArticleInternational journal of molecular sciences2022

A Food-Grade Method for Enhancing the Levels of Low Molecular Weight Proanthocyanidins with Potentially High Intestinal Bioavailability.

Fortuna Iannuzzo, Vincenzo Piccolo, Ettore Novellino, Elisabetta Schiano, Emanuela Salviati, Vincenzo Summa, Pietro Campiglia, Gian Carlo Tenore, Maria Maisto

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Cells · 2026
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  15. Natural Chalcones for the Management of Obesity Disease.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Fortuna IannuzzoDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 59, 80131 Naples, Italy.
Vincenzo PiccoloDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 59, 80131 Naples, Italy.ORCID 0000-0003-4480-5022
Ettore NovellinoFaculty of Medicine and Surgery, Catholic University of the Sacred Heart, 00168 Rome, Italy.
Elisabetta SchianoDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 59, 80131 Naples, Italy.ORCID 0000-0002-8167-0334
Emanuela SalviatiDepartment of Pharmacy, School of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Salerno, Italy.ORCID 0000-0003-2867-2784
Vincenzo SummaDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 59, 80131 Naples, Italy.ORCID 0000-0002-6288-2681
Pietro CampigliaDepartment of Pharmacy, School of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Salerno, Italy.ORCID 0000-0002-1069-2181
Gian Carlo TenoreDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 59, 80131 Naples, Italy.ORCID 0000-0002-0251-9936
Maria MaistoDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 59, 80131 Naples, Italy.ORCID 0000-0002-0340-2254
University of Naples Federico II · ITUniversity of Salerno · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proanthocyanidins (PACs) are a group of bioactive molecules found in a variety of plants and foods. Their bioavailability depends on their molecular size, with monomers and dimers being more bioavailable than those that have a higher polymerization degree. This study aimed to develop a method to convert high-molecular-weight PACs to low-molecular-weight ones in a grape seed extract (GSE) from

Indexed as

Grape Seed ExtractProanthocyanidinsVitisBiological AvailabilityMolecular WeightPlant ExtractsSeedsGrape Seed ExtractPlant ExtractsProanthocyanidinsantioxidantgrape seedsLC/MS analysisproanthocyanidinsVitis vinifera

Identifiers

PMID36362344
PMCPMC9657391
OpenAlexW4308509805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.