Evidence map›Paper›PMID 36362293›Full record

ReviewInternational journal of molecular sciences2022

Cyclodextrin-Based Polymeric Materials Bound to Corona Protein for Theranostic Applications.

Donya Esmaeilpour, Jens Albert Broscheit, Sergey Shityakov

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. β‑Cyclodextrin-CoatedACS applied nano materials · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Cyclodextrins for Lithium Batteries Applications.Materials (Basel, Switzerland) · 2023
    Review
  8. A Review on Cyclodextrins/Estrogens Inclusion Complexes.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Donya EsmaeilpourDepartment of Chemistry, University of Isfahan, Isfahan 8174673441, Iran.
Jens Albert BroscheitDepartment of Anesthesiology and Critical Care, University of Wuerzburg, Oberduerrbacher Str. 6, 97080 Wurzburg, Germany.ORCID 0000-0002-6272-2960
Sergey ShityakovLaboratory of Chemoinformatics, Infochemistry Scientific Center, ITMO University, 191002 Saint-Petersburg, Russia.ORCID 0000-0002-6953-9771

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclodextrins (CDs) are cyclic oligosaccharide structures that could be used for theranostic applications in personalized medicine. These compounds have been widely utilized not only for enhancing drug solubility, stability, and bioavailability but also for controlled and targeted delivery of small molecules. These compounds can be complexed with various biomolecules, such as peptides or proteins, via host-guest interactions. CDs are amphiphilic compounds with water-hating holes and water-absorbing surfaces. Architectures of CDs allow the drawing and preparation of CD-based polymers (CDbPs) with optimal pharmacokinetic and pharmacodynamic properties. These polymers can be cloaked with protein corona consisting of adsorbed plasma or extracellular proteins to improve nanoparticle biodistribution and half-life. Besides, CDs have become famous in applications ranging from biomedicine to environmental sciences. In this review, we emphasize ongoing research in biomedical fields using CD-based centered, pendant, and terminated polymers and their interactions with protein corona for theranostic applications. Overall, a perusal of information concerning this novel approach in biomedicine will help to implement this methodology based on host-guest interaction to improve therapeutic and diagnostic strategies.

Indexed as

CyclodextrinsProtein CoronaDrug Delivery SystemsPharmaceutical PreparationsPolymersPrecision MedicineTissue DistributionWaterCyclodextrinsPharmaceutical PreparationsPolymersProtein CoronaWatercyclodextrinnanomedicinepolymersprotein coronatheranosticstherapy

Identifiers

PMID36362293
PMCPMC9656986

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.