Evidence map›Paper›PMID 36362213›Full record

ArticleInternational journal of molecular sciences2022

Characteristics of BRCA2 Mutated Prostate Cancer at Presentation.

Hyunho Han, Cheol Keun Park, Nam Hoon Cho, Jongsoo Lee, Won Sik Jang, Won Sik Ham, Young Deuk Choi, Kang Su Cho

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Clinical Significance of Germline Variants in theCancer control : journal of the Moffitt Cancer Center
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hyunho HanDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul 03722, Korea.
Cheol Keun ParkPathology Center, Seegene Medical Foundation, Seoul 04805, Korea.ORCID 0000-0001-7689-0386
Nam Hoon ChoDepartment of Pathology, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0002-0045-6441
Jongsoo LeeDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0002-9984-1138
Won Sik JangDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0002-9082-0381
Won Sik HamDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0003-2246-8838
Young Deuk ChoiDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0002-8545-5797
Kang Su ChoDepartment of Urology, Prostate Cancer Center, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06229, Korea.ORCID 0000-0002-3500-8833
Yonsei University · KR

Funding

Korea Health Industry Development Institute HI19C0723
6 · The paper itself

Abstract

Genetic alterations of DNA repair genes, particularly BRCA2 in patients with prostate cancer, are associated with aggressive behavior of the disease. It has reached consensus that somatic and germline tests are necessary when treating advanced prostate cancer patients. Yet, it is unclear whether the mutations are associated with any presenting clinical features. We assessed the incidences and characteristics of

Indexed as

Germ-Line MutationProstatic NeoplasmsBRCA2 ProteinGenes, BRCA2HumansMaleMutationBRCA2 ProteinBRCA2 protein, humanBRCA2prostate cancerPSA

Identifiers

PMID36362213
PMCPMC9659116
OpenAlexW4308333455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.