Evidence map›Paper›PMID 36362200›Full record

ArticleInternational journal of molecular sciences2022

Genomic Determinants Potentially Associated with Clinical Manifestations of Human-Pathogenic Tick-Borne Flaviviruses.

Artem N Bondaryuk, Nina V Kulakova, Ulyana V Potapova, Olga I Belykh, Anzhelika V Yudinceva, Yurij S Bukin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Artem N BondaryukLaboratory of Natural Focal Viral Infections, Irkutsk Antiplague Research Institute of Siberia and the Far East, 664047 Irkutsk, Russia.ORCID 0000-0003-4422-0497
Nina V KulakovaDepartment of Biodiversity and Biological Resources, Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch of the Russian Academy of Sciences, 664033 Irkutsk, Russia.ORCID 0000-0001-5762-8817
Ulyana V PotapovaLimnological Institute, Siberian Branch of the Russian Academy of Sciences, 664033 Irkutsk, Russia.
Olga I BelykhLimnological Institute, Siberian Branch of the Russian Academy of Sciences, 664033 Irkutsk, Russia.ORCID 0000-0002-1188-7351
Anzhelika V YudincevaLimnological Institute, Siberian Branch of the Russian Academy of Sciences, 664033 Irkutsk, Russia.
Yurij S BukinLimnological Institute, Siberian Branch of the Russian Academy of Sciences, 664033 Irkutsk, Russia.ORCID 0000-0002-4534-3846
Siberian Branch of the Russian Academy of Sciences · RUSiberian Institute of Plant Physiology and Biochemistry · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tick-borne flavivirus group contains at least five species that are pathogenic to humans, three of which induce encephalitis (tick-borne encephalitis virus, louping-ill virus, Powassan virus) and another two species induce hemorrhagic fever (Omsk hemorrhagic fever virus, Kyasanur Forest disease virus). To date, the molecular mechanisms responsible for these strikingly different clinical forms are not completely understood. Using a bioinformatic approach, we performed the analysis of each amino acid (aa) position in the alignment of 323 polyprotein sequences to calculate the fixation index (

Indexed as

Encephalitis Viruses, Tick-BorneTicksAnimalsComputational BiologyGenomicsHumansViral ProteinsViral Proteinscell tropismencephalitisfixation indexhemorrhagic fevertick-borne flavivirusestissue tropism

Identifiers

PMID36362200
PMCPMC9658301
OpenAlexW4309090847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.