Evidence map›Paper›PMID 36362197›Full record

ArticleInternational journal of molecular sciences2022

MED1 Ablation Promotes Oral Mucosal Wound Healing via JNK Signaling Pathway.

Zhaosong Meng, Zhe Li, Shuling Guo, Danfeng Wu, Ran Wei, Jiacheng Liu, Lizhi Hu, Lei Sui

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zhaosong MengSchool of Stomatology, Tianjin Medical University, Tianjin 300014, China.ORCID 0000-0002-8977-8446
Zhe LiSchool of Stomatology, Tianjin Medical University, Tianjin 300014, China.ORCID 0000-0002-7741-9462
Shuling GuoSchool of Stomatology, Tianjin Medical University, Tianjin 300014, China.
Danfeng WuSchool of Stomatology, Tianjin Medical University, Tianjin 300014, China.
Ran WeiSchool of Stomatology, Tianjin Medical University, Tianjin 300014, China.
Jiacheng LiuSchool of Stomatology, Tianjin Medical University, Tianjin 300014, China.
Lizhi HuImmunology Department, Key Laboratory of Immune Microenvironment and Disease, Ministry of Education, Tianjin Medical University, Tianjin 300014, China.
Lei SuiSchool of Stomatology, Tianjin Medical University, Tianjin 300014, China.
Tianjin Medical University · CN

Funding

National Natural Science Foundation of China 81700927National Natural Science Foundation of China 81970958Tianjin Municipal Science and Technology Commission 21JCQNJC01190
6 · The paper itself

Abstract

Mediator complex subunit 1 (MED1) is a coactivator of multiple transcription factors and plays a key role in regulating epidermal homeostasis as well as skin wound healing. It is unknown, however, whether it plays a role in healing oral mucosal wounds. In this study, we investigate MED1's functional effects on oral mucosal wound healing and its underlying mechanism. The epithelial-specific MED1 null (Med1

Indexed as

MAP Kinase Signaling SystemWound HealingAnimalsCell MovementEpidermisKeratinocytesMediator Complex Subunit 1MiceRe-EpithelializationMed1 protein, mouseMediator Complex Subunit 1activin AJNK signaling pathwayMED1oral mucosawound healing

Identifiers

PMID36362197
PMCPMC9655393
OpenAlexW4308721067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.