Evidence map›Paper›PMID 36362126›Full record

ArticleInternational journal of molecular sciences2022

Clinical Study of the Relationship between Sjögren Syndrome and T-Cell Large Granular Lymphocytic Leukemia: Single-Center Experience.

Vadim Gorodetskiy, Vladimir Vasilyev, Yulia Sidorova, Bella Biderman, Natalia Kupryshina, Murad Vagida, Natalya Ryzhikova, Andrey Sudarikov

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Large granular lymphocyte leukemia: a clonal disorder with autoimmune manifestations.Hematology. American Society of Hematology. Education Program · 2024
    Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Vadim GorodetskiyDepartment of Intensive Methods of Therapy, V.A. Nasonova Research Institute of Rheumatology, 115522 Moscow, Russia.ORCID 0000-0001-8428-1281
Vladimir VasilyevJoint and Heart Treatment Center, 107140 Moscow, Russia.
Yulia SidorovaLaboratory of Molecular Hematology, National Medical Research Center for Hematology, 125167 Moscow, Russia.
Bella BidermanLaboratory of Molecular Hematology, National Medical Research Center for Hematology, 125167 Moscow, Russia.ORCID 0000-0002-6253-3334
Natalia KupryshinaHematopoiesis Immunology Laboratory, Russian Cancer Research Center N.N. Blokhin, 115478 Moscow, Russia.
Murad VagidaLaboratory of Transplantation Immunology, National Medical Research Center for Hematology, 125167 Moscow, Russia.ORCID 0000-0001-7408-3994
Natalya RyzhikovaLaboratory of Molecular Hematology, National Medical Research Center for Hematology, 125167 Moscow, Russia.
Andrey SudarikovLaboratory of Molecular Hematology, National Medical Research Center for Hematology, 125167 Moscow, Russia.ORCID 0000-0001-9463-9187
National Medical Research Center for Hematology · RUAssociation of Rheumatologists of Russia · RURussian Cancer Research Center NN Blokhin · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between Sjögren syndrome (SS) and T-cell large granular lymphocytic (T-LGL) leukemia remains unclear. In this paper, we report for the first time a large case series of 21 patients with primary and secondary SS associated with T-LGL leukemia. Our results suggest the importance of considering T-LGL leukemia in the diagnostic evaluation of SS patients, particularly when neutropenia occurs. We also postulate that elevated antinuclear antibody titers in patients with T-LGL leukemia indicate the need for the clinical assessment of SS. To assess whether SS affects the frequency of the signal transducer and activator of transcription 3 (

Indexed as

Leukemia, Large Granular LymphocyticNeutropeniaSjogren's SyndromeHigh-Throughput Nucleotide SequencingHumansMutationimmunophenotypingnext-generation sequencingSjögren syndromeSTAT3 mutationT-cell large granular lymphocytic leukemia

Identifiers

PMID36362126
PMCPMC9656665
OpenAlexW4308124064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.