Evidence map›Paper›PMID 36362109›Full record

ReviewInternational journal of molecular sciences2022

Vertebrate Animal Models of RP59: Current Status and Future Prospects.

Steven J Fliesler, Sriganesh Ramachandra Rao, Mai N Nguyen, Mahmoud Tawfik KhalafAllah, Steven J Pittler

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Steven J FlieslerDepartments of Ophthalmology and Biochemistry, Neuroscience Graduate Program, Jacobs School of Medicine, State University of New York-University at Buffalo, Buffalo, NY 14203, USA.ORCID 0000-0002-2557-142X
Sriganesh Ramachandra RaoDepartments of Ophthalmology and Biochemistry, Neuroscience Graduate Program, Jacobs School of Medicine, State University of New York-University at Buffalo, Buffalo, NY 14203, USA.ORCID 0000-0003-1029-1051
Mai N NguyenDepartment of Optometry and Vision Science, Vision Science Research Center, School of Optometry, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Mahmoud Tawfik KhalafAllahDepartment of Optometry and Vision Science, Vision Science Research Center, School of Optometry, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Steven J PittlerDepartment of Optometry and Vision Science, Vision Science Research Center, School of Optometry, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-8464-9303
University of Alabama at Birmingham · USVA Western New York Healthcare System · US

Funding

Visual Phenotyping CoreP30EY003039 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Paul Douglas Gamlin · 1985 to 2026
$16.9M
Development and characterization of mouse models of RP59 DHDDS deficiencyR01EY029341 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FLIESLER, STEVEN J., PITTLER, STEVEN J · 2018 to 2021
$2.2M
Characterization of DHDDS RP59 Knockin Models of Retinitis PigmentosaF31EY032764 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI NGUYEN, MAI N · 2021 to 2025
$198k
NEI NIH HHS F31 EY032764NEI NIH HHS P30 EY003039NIH HHS R01 EY029341VA I K6 BX005787
6 · The paper itself

Abstract

Retinitis pigmentosa-59 (RP59) is a rare, recessive form of RP, caused by mutations in the gene encoding DHDDS (dehydrodolichyl diphosphate synthase). DHDDS forms a heterotetrameric complex with Nogo-B receptor (NgBR; gene

Indexed as

Alkyl and Aryl TransferasesAnimalsDolicholsMiceModels, AnimalMutationVertebratesAlkyl and Aryl TransferasesDolicholscis-prenyltransferaseDHDDSdolicholnogo-B receptorretinal degenerationRP59

Identifiers

PMID36362109
PMCPMC9657489
OpenAlexW4308127929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.