Evidence map›Paper›PMID 36362059›Full record

ArticleInternational journal of molecular sciences2022

Cell-Free Hemoglobin in Acute Kidney Injury after Lung Transplantation and Experimental Renal Ischemia/Reperfusion.

Robert Greite, Li Wang, Lukas Gohlke, Sebastian Schott, Kirill Kreimann, Julian Doricic, Andreas Leffler, Igor Tudorache, Jawad Salman, Ruslan Natanov and 13 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Molecular Frontiers in Transplantation-Induced Ischemia-Reperfusion Injury.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 4 institutions in 3 countries.

Robert GreiteDepartment of Nephrology and Hypertension, Hannover Medical School, 30625 Hannover, Germany.
Li WangDepartment of Nephrology and Hypertension, Hannover Medical School, 30625 Hannover, Germany.
Lukas GohlkeDepartment of Nephrology and Hypertension, Hannover Medical School, 30625 Hannover, Germany.
Sebastian SchottDepartment of Nephrology and Hypertension, Hannover Medical School, 30625 Hannover, Germany.
Kirill KreimannDepartment of Nephrology and Hypertension, Hannover Medical School, 30625 Hannover, Germany.
Julian DoricicDepartment of Nephrology and Hypertension, Hannover Medical School, 30625 Hannover, Germany.
Andreas LefflerAnaesthesiology, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0003-1121-6387
Igor TudoracheCardiac Surgery, University of Dusseldorf, 40225 Dusseldorf, Germany.
Jawad SalmanCardiac Surgery, Hannover Medical School, 30625 Hannover, Germany.
Ruslan NatanovCardiac Surgery, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0003-2219-3766
Fabio IusCardiac Surgery, Hannover Medical School, 30625 Hannover, Germany.
Christine FegbeutelCardiac Surgery, Hannover Medical School, 30625 Hannover, Germany.
Axel HaverichCardiac Surgery, Hannover Medical School, 30625 Hannover, Germany.
Ralf LichtinghagenClinical Chemistry, Hannover Medical School, 30625 Hannover, Germany.
Rongjun ChenDepartment of Nephrology and Hypertension, Hannover Medical School, 30625 Hannover, Germany.
Song RongDepartment of Nephrology and Hypertension, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0001-9985-1515
Hermann HallerDepartment of Nephrology and Hypertension, Hannover Medical School, 30625 Hannover, Germany.
Vijith VijayanPediatrics, Stanford University, Stanford, CA 94305, USA.
Magnus GramDepartment of Pediatrics, Clinical Sciences Lund, Lund University, 22220 Lund, Sweden.ORCID 0000-0002-5880-2925
Irina ScheffnerDepartment of Nephrology and Hypertension, Hannover Medical School, 30625 Hannover, Germany.
Faikah GuelerDepartment of Nephrology and Hypertension, Hannover Medical School, 30625 Hannover, Germany.
Wilfried GwinnerDepartment of Nephrology and Hypertension, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0003-1703-893X
Stephan ImmenschuhInstitute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, 30625 Hannover, Germany.
Medizinische Hochschule Hannover · DEHeinrich Heine University Düsseldorf · DELund University · SEStanford University · US

Funding

Deutsche Forschungsgemeinschaft GU 613/1-1Deutsche Forschungsgemeinschaft IM 20/4-1Federal Ministry of Education and Research 03INT502AB
6 · The paper itself

Abstract

Cell-free hemoglobin (CFH), a pro-oxidant and cytotoxic compound that is released in hemolysis, has been associated with nephrotoxicity. Lung transplantation (LuTx) is a clinical condition with a high incidence of acute kidney injury (AKI). In this study, we investigated the plasma levels of CFH and haptoglobin, a CFH-binding serum protein, in prospectively enrolled LuTx patients (

Indexed as

Acute Kidney InjuryHemoglobinsLung TransplantationReperfusion InjuryAnimalsCreatinineHaptoglobinsIschemiaKidneyMiceReperfusionCreatinineHaptoglobinsHemoglobinsacute kidney injuryfree hemoglobinhemolysislung transplantation

Identifiers

PMID36362059
PMCPMC9657083
OpenAlexW4308120118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.