Evidence map›Paper›PMID 36361959›Full record

ArticleInternational journal of molecular sciences2022

Identification of

Aurora Mazzei, Grazia Serino, Alessandro Romano, Emanuele Piccinno, Viviana Scalavino, Anna Maria Valentini, Raffaele Armentano, Roberta Schiavone, Gianluigi Giannelli, Tiziano Verri and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Aurora MazzeiDepartment of Biological and Environmental Sciences and Technologies (DeBEST), University of Salento, 73100 Lecce, Italy.
Grazia SerinoNational Institute of Gastroenterology “S. de Bellis”, IRCCS Research Hospital, 70013 Castellana Grotte, Italy.ORCID 0000-0002-2971-0802
Alessandro RomanoDivision of Neuroscience, Experimental Neurology Unit, San Raffaele Scientific Institute, 20132 Milano, Italy.
Emanuele PiccinnoNational Institute of Gastroenterology “S. de Bellis”, IRCCS Research Hospital, 70013 Castellana Grotte, Italy.ORCID 0000-0002-7988-1917
Viviana ScalavinoNational Institute of Gastroenterology “S. de Bellis”, IRCCS Research Hospital, 70013 Castellana Grotte, Italy.ORCID 0000-0002-0273-2825
Anna Maria ValentiniNational Institute of Gastroenterology “S. de Bellis”, IRCCS Research Hospital, 70013 Castellana Grotte, Italy.ORCID 0000-0002-6798-808X
Raffaele ArmentanoNational Institute of Gastroenterology “S. de Bellis”, IRCCS Research Hospital, 70013 Castellana Grotte, Italy.ORCID 0000-0003-1661-5504
Roberta SchiavoneDepartment of Biological and Environmental Sciences and Technologies (DeBEST), University of Salento, 73100 Lecce, Italy.
Gianluigi GiannelliNational Institute of Gastroenterology “S. de Bellis”, IRCCS Research Hospital, 70013 Castellana Grotte, Italy.
Tiziano VerriDepartment of Biological and Environmental Sciences and Technologies (DeBEST), University of Salento, 73100 Lecce, Italy.ORCID 0000-0003-4983-2767
Amilcare BarcaDepartment of Biological and Environmental Sciences and Technologies (DeBEST), University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-3117-2724
Gastroenterology Hospital "Saverio de Bellis" · ITUniversity of Salento · ITSan Raffaele University of Rome · IT

Funding

Italian Ministry of Health [Ricerca Corrente 2022]Italian Ministry of University and Research [ex 60%]
6 · The paper itself

Abstract

SLC15A4/PHT1 is an endolysosome-resident carrier of oligopeptides and histidine recently come into view as a key path marker of immune/autoimmune/inflammatory pathways in immune cells. Yet, its emerging role in inflammatory processes directly targeting the gastrointestinal epithelial layer, as in the multifactorial pathophysiology of inflammatory bowel disease (IBD), is poorly investigated. Here, the first identification of

Indexed as

Colitis, UlcerativeInflammatory Bowel DiseasesMembrane Transport ProteinsAnimalsCaco-2 CellsColitisColonDextran SulfateHumansIntestinal MucosaMiceMice, Inbred C57BLNerve Tissue ProteinsUp-RegulationDextran SulfateMembrane Transport ProteinsNerve Tissue ProteinsSLC15A4 protein, humanenterocytesIBDinflammationSLC15A4/PHT1ulcerative colitis

Identifiers

PMID36361959
PMCPMC9658943
OpenAlexW4307946133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.