Evidence map›Paper›PMID 36361957›Full record

ArticleInternational journal of molecular sciences2022

Differential Response of Transcription Factors to Activated Kinases in Steroidogenic and Non-Steroidogenic Cells.

Kenley Joule Pierre, Jacques J Tremblay

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. A 35-bp Conserved Region Is Crucial forInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kenley Joule PierreReproduction, Mother and Child Health, Room T3-67, CHU de Québec-Université Laval Research Centre, Québec, QC G1V 4G2, Canada.
Jacques J TremblayReproduction, Mother and Child Health, Room T3-67, CHU de Québec-Université Laval Research Centre, Québec, QC G1V 4G2, Canada.ORCID 0000-0002-4738-6284
Université Laval · CA

Funding

CIHR MOP-81387
6 · The paper itself

Abstract

Hormone-induced Leydig cell steroidogenesis requires rapid changes in gene expression in response to various hormones, cytokines, and growth factors. These proteins act by binding to their receptors on the surface of Leydig cells leading to activation of multiple intracellular signaling cascades, downstream of which are several kinases, including protein kinase A (PKA), Ca

Indexed as

PhosphoproteinsTranscription FactorsCalcium-Calmodulin-Dependent Protein Kinase Type 1Cyclic AMP-Dependent Protein KinasesHormonesHumansLeydig CellsMaleMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Calcium-Calmodulin-Dependent Protein Kinase Type 1Cyclic AMP-Dependent Protein KinasesHormonesMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3PhosphoproteinsTranscription FactorsbZIP factorsCAMKIERK1/2GATA4Leydig cellsMEF2 factorsNuclear receptorsPKAsignaling cascadeSteroidogenesis

Identifiers

PMID36361957
PMCPMC9658689
OpenAlexW4307945778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.