Evidence map›Paper›PMID 36361875›Full record

ArticleInternational journal of molecular sciences2022

Availability of Ferritin-Bound Iron to Enterobacteriaceae.

Clemens M Gehrer, Alexander Hoffmann, Richard Hilbe, Philipp Grubwieser, Anna-Maria Mitterstiller, Heribert Talasz, Ferric C Fang, Esther G Meyron-Holtz, Sarah H Atkinson, Günter Weiss and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 5 countries.

Clemens M GehrerDepartment of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-9454-6375
Alexander HoffmannDepartment of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Richard HilbeDepartment of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Philipp GrubwieserDepartment of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-6233-8910
Anna-Maria MitterstillerDepartment of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-9338-5135
Heribert TalaszBiocenter, Institute of Medical Biochemistry, Medical Universitiy of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-4555-718X
Ferric C FangDepartment of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA 98195-7110, USA.ORCID 0000-0002-3243-110X
Esther G Meyron-HoltzLaboratory of Molecular Nutrition, Faculty of Biotechnology and Food Engineering, Technion-Israel Institute of Technology, Haifa 32000, Israel.
Sarah H AtkinsonKenya Medical Research Institute (KEMRI), Centre for Geographic Medicine Research Coast, KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
Günter WeissDepartment of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-0709-2158
Manfred NairzDepartment of Internal Medicine II, Infectious Diseases, Immunology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Innsbruck Medical University · ATKenya Medical Research Institute · KETechnion – Israel Institute of Technology · ILUniversity of Washington · US

Funding

FWF Austrian Science Fund P 33062-B
6 · The paper itself

Abstract

The sequestration of iron in case of infection, termed nutritional immunity, is an established strategy of host defense. However, the interaction between pathogens and the mammalian iron storage protein ferritin is hitherto not completely understood. To better characterize the function of ferritin in Gram-negative infections, we incubated iron-starved cultures of

Indexed as

FerritinsIronAnimalsCattleEnterobacteriaceaeEscherichia coliHorsesMammalsSalmonella typhimuriumSuperoxide DismutaseFerritinsIronSuperoxide DismutaseEscherichia coliferritiniron metabolismnutritional immunityreactive oxygen speciesSalmonella enterica subsp. enterica serovar Typhimuriumsiderophoresuperoxide dismutase

Identifiers

PMID36361875
PMCPMC9657528
OpenAlexW4307946124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.