Evidence map›Paper›PMID 36361758›Full record

ReviewInternational journal of molecular sciences2022

Old and New Blood Markers in Human Colorectal Cancer.

Jean-Luc Wautier, Marie-Paule Wautier

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. The emerging roles of CEACAM6 in human cancer (Review).International journal of oncology · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Pro- and Anti-Inflammatory Prostaglandins and Cytokines in Humans:International journal of molecular sciences · 2023
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jean-Luc WautierFaculté de Médecine, Université Denis Diderot Paris, 75013 Paris, France.ORCID 0000-0001-6826-2312
Marie-Paule WautierFaculté de Médecine, Université Denis Diderot Paris, 75013 Paris, France.
Délégation Paris 7 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a predominant cause of mortality all over the world. Lung, prostate, and colorectal cancer are the more frequent in men while breast and colorectal have a high incidence in women. Major progress aside, some cancers are still frequent and one major issue is improvements in detection methods. Imaging techniques have a major role, but inflammatory, tumoral markers and calculated scores may contribute to the assessment of prognosis. The erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and carcinoembryonic antigen cell adhesion molecule (CEACAM) have been used for decades and do not have a clear use for diagnosis or prognosis yet. The CEACAM family includes 12 human members, and some of them have a cluster differentiation (CD). CD66 may be an interesting indicator of disease severity. Beside interleukin-6 (IL-6), the high level of which is observed in patients with a high mortality rate, other cytokines IL-17A, IL-22, and transforming growth factor -β (TGF-β) are expressed at the tumor level. The detection of circulating tumor cells has been improved but is still of undetermined value. Circulating tumor DNA (ctDNA) was recently studied in CRC stage II patients and may be helpful for chemotherapy management.

Indexed as

Circulating Tumor DNAColorectal NeoplasmsNeoplastic Cells, CirculatingBiomarkers, TumorCarcinoembryonic AntigenC-Reactive ProteinFemaleHumansMaleBiomarkers, TumorCarcinoembryonic AntigenCirculating Tumor DNAC-Reactive Proteincarcinoembryonic antigen (CEA)CEA cell adhesion molecule (CEACAM)circulating tumor cellscirculating tumor DNAcolorectal cancer (CRC)C-reactive protein (CRP)interleukinsmatrix metalloproteinases (MMPs)

Identifiers

PMID36361758
PMCPMC9656373
OpenAlexW4307301695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.