Evidence map›Paper›PMID 36361588›Full record

ArticleInternational journal of molecular sciences2022

Does Vitamin D Work Synergistically with Anti-Asthmatic Drugs in Airway Remodeling?

Marharyta Sobczak, Rafał Pawliczak

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Role and regulators of NFrontiers in pharmacology · 2024
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marharyta SobczakDepartment of Immunopathology, Division of Biomedical Science, Faculty of Medicine, Medical University of Lodz, 90-752 Lodz, Poland.ORCID 0000-0002-2244-7730
Rafał PawliczakDepartment of Immunopathology, Division of Biomedical Science, Faculty of Medicine, Medical University of Lodz, 90-752 Lodz, Poland.ORCID 0000-0001-6784-453X
Medical University of Lodz · PL

Funding

Medical University of Lodz 503/0-149-03/503-01-001-19-00National Centre for Research and Development in the framework of the project InterChemMed, co-financed by the European Social Fund POWR.03.02.00-00-I029/16
6 · The paper itself

Abstract

Vitamin D is commonly known for its properties of airway remodeling inhibition. Due to this, we decided to analyze the action of calcitriol with anti-asthmatic drugs in airway remodeling. The HFL1 cell line was treated with calcitriol, beclomethasone 17-propionate, montelukast sodium, LTD4 and TGF-β in different combinations. Real-time PCR was used to analyzed the expression of ACTA2, CDH-1, Vimentin, ADAM33, MMP-9 and CysLTR1 on the mRNA level, whereas Western blot was used to analyze gene expression on the protein level. One-way analysis variants, the Kruskal-Wallis test, Student's

Indexed as

Airway RemodelingAnti-Asthmatic AgentsAcetatesADAM ProteinsCalcitriolCyclopropanesHumansLeukotriene D4QuinolinesSulfidesTransforming Growth Factor betaVimentinVitamin DVitaminsAcetatesADAM33 protein, humanADAM ProteinsAnti-Asthmatic AgentsCalcitriolCyclopropanesLeukotriene D4montelukastQuinolinesSulfidesTransforming Growth Factor betaVimentinVitamin DVitamins1,25(OH)2D3airway remodelingbronchial asthmacalcitriolvitamin D

Identifiers

PMID36361588
PMCPMC9656909
OpenAlexW4308118691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.