Evidence map›Paper›PMID 36361570›Full record

ArticleInternational journal of molecular sciences2022

A Pyrazolate Osmium(VI) Nitride Exhibits Anticancer Activity through Modulating Protein Homeostasis in HepG2 Cells.

Chengyang Huang, Wanqiong Huang, Pengchao Ji, Fuling Song, Tao Liu, Meiyang Li, Hongzhi Guo, Yongliang Huang, Cuicui Yu, Chuanxian Wang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Chengyang HuangDepartment of Physiology, Shantou University Medical College, Shantou 515041, China.ORCID 0000-0003-4021-0726
Wanqiong HuangDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou 515041, China.
Pengchao JiDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou 515041, China.
Fuling SongDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou 515041, China.
Tao LiuDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou 515041, China.
Meiyang LiDepartment of Physiology, Shantou University Medical College, Shantou 515041, China.
Hongzhi GuoDepartment of Physiology, Shantou University Medical College, Shantou 515041, China.
Yongliang HuangDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou 515041, China.
Cuicui YuDepartment of Physiology, Shantou University Medical College, Shantou 515041, China.
Chuanxian WangDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou 515041, China.
Wenxiu NiDepartment of Medicinal Chemistry, Shantou University Medical College, Shantou 515041, China.ORCID 0000-0002-2370-6300
Shantou University · CNUniversity of California, Los Angeles · US

Funding

Guangdong Major Project of Basic and Applied Basic Research 2019B030302009
6 · The paper itself

Abstract

Interest in the third-row transition metal osmium and its compounds as potential anticancer agents has grown in recent years. Here, we synthesized the osmium(VI) nitrido complex

Indexed as

Antineoplastic AgentsOsmiumApoptosisCell Line, TumorHep G2 CellsHumansProteostasisAntineoplastic AgentsOsmiumanticancerapoptosisosmium complexprotein homeostasispyrazole derivatives

Identifiers

PMID36361570
PMCPMC9656236
OpenAlexW4307273299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.