Evidence map›Paper›PMID 36361555›Full record

ArticleInternational journal of molecular sciences2022

Hydroxygenkwanin Improves the Efficacy of Cytotoxic Drugs in ABCG2-Overexpressing Multidrug-Resistant Cancer Cells.

Yan-Qing Li, Megumi Murakami, Yang-Hui Huang, Tai-Ho Hung, Shun-Ping Wang, Yu-Shan Wu, Suresh V Ambudkar, Chung-Pu Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Yan-Qing LiGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Megumi MurakamiLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Yang-Hui HuangGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Tai-Ho HungDepartment of Obstetrics and Gynecology, Taipei Chang Gung Memorial Hospital, Taipei 10507, Taiwan.
Shun-Ping WangDepartment of Orthopedics, Taichung Veterans General Hospital, Taichung 40704, Taiwan.
Yu-Shan WuDepartment of Chemistry, Tunghai University, Taichung 40704, Taiwan.ORCID 0000-0003-4027-0710
Suresh V AmbudkarLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.ORCID 0000-0002-2639-4955
Chung-Pu WuGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-2434-3361
Chang Gung University · TWNational Cancer Institute · USTaichung Veterans General Hospital · TWTunghai University · TW

Funding

Chang Gung Memorial Hospital BMRPC17Chang Gung Memorial Hospital CMRPD1J0283Chang Gung Memorial Hospital CMRPG1J0073Chang Gung Memorial Hospital CORPG1L0051Chang Gung Memorial Hospital CORPG2L0031National Cancer Institute, Center for Cancer Research Intramural Research Program of the National Institutes of HealthTaichung Veterans General Hospital TCVGH-T1107807The Ministry of Science and Technology, Taiwan MOST-108-2320-B-182-038-MY3The Ministry of Science and Technology, Taiwan MOST-109-2113-M-029-007The Ministry of Science and Technology, Taiwan MOST-109-2314-B-182A-097-MY3The Ministry of Science and Technology, Taiwan MOST-111-2320-B-182-018
6 · The paper itself

Abstract

Hydroxygenkwanin, a flavonoid isolated from the leaves of the

Indexed as

Antineoplastic AgentsNeoplasmsATP-Binding Cassette TransportersATP Binding Cassette Transporter, Subfamily G, Member 2Cell Line, TumorDrug Resistance, MultipleDrug Resistance, NeoplasmFlavonoidsHumansNeoplasm ProteinsABCG2 protein, humanAntineoplastic AgentsATP-Binding Cassette TransportersATP Binding Cassette Transporter, Subfamily G, Member 2FlavonoidshydroxygenkwaninNeoplasm ProteinsABCG2ABC-transporterchemosensitizerhydroxygenkwaninmultidrug resistancenatural products

Identifiers

PMID36361555
PMCPMC9658017
OpenAlexW4307370108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.