Evidence map›Paper›PMID 36361537›Full record

ArticleInternational journal of molecular sciences2022

Live or Heat-Killed

Valentino Le Noci, Giancarla Bernardo, Giacomo Manenti, Gabriele Infante, Dariush Khaleghi Hashemian, Lucia Minoli, Simone Canesi, Francesca Bianchi, Tiziana Triulzi, Stefania Arioli and 8 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Valentino Le NociDipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-7470-6909
Giancarla BernardoDipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, 20133 Milan, Italy.
Giacomo ManentiAnimal Health and Welfare Unit, Department of Applied Research and Technical Development, Fondazione IRCCS Istituto Nazionale Tumori, 20133 Milan, Italy.
Gabriele InfanteLaboratory of Medical Statistics and Biometry "Giulio A. Maccacaro", Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0001-7505-5784
Dariush Khaleghi HashemianLaboratory of Medical Statistics and Biometry "Giulio A. Maccacaro", Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0002-1881-231X
Lucia MinoliDipartimento di Scienze Veterinarie, Università degli Studi di Torino, 10095 Turin, Italy.ORCID 0000-0001-8938-4319
Simone CanesiMouse and Animal Pathology Laboratory (MAPLab), Fondazione Unimi, 20139 Milan, Italy.
Francesca BianchiDipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0001-5197-5279
Tiziana TriulziMolecular Targeting Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.ORCID 0000-0003-3050-8676
Stefania ArioliDipartimento di Scienze per gli Alimenti, la Nutrizione e l'Ambiente (DeFENS), Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-5406-8268
Loris De CeccoMolecular Mechanisms Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.ORCID 0000-0002-7066-473X
Simone GuglielmettiDipartimento di Scienze per gli Alimenti, la Nutrizione e l'Ambiente (DeFENS), Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-8673-8190
Federico AmbrogiLaboratory of Medical Statistics and Biometry "Giulio A. Maccacaro", Department of Clinical Sciences and Community Health, Università degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0001-9358-011X
Camilla RecordatiMouse and Animal Pathology Laboratory (MAPLab), Fondazione Unimi, 20139 Milan, Italy.ORCID 0000-0002-7172-9662
Nicoletta GaglianoDipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-3393-3144
Elda TagliabueMolecular Targeting Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.ORCID 0000-0001-9877-2903
Michele SommarivaDipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-7622-0996
Lucia SfondriniDipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0003-0350-5402
University of Milan · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITUniversity of Turin · IT

Funding

Bando Ricerca Istituzionale 2018 Cod. Id. D/17/1NO - Fondi 5x1000 Ministero della Salute 2015Italian Association for Cancer Research IG 2020 - ID. 24718 project
6 · The paper itself

Abstract

An immunosuppressive microenvironment in lung concurs to pre-malignant lesions progression to cancer. Here, we explore if perturbing lung microbiota, which contribute to immunosuppression, by antibiotics or probiotic aerosol interferes with lung cancer development in a mouse carcinogen-induced tumor model. Urethane-injected mice were vancomycin/neomycin (V/N)-aerosolized or live or dead

Indexed as

AdenomaLacticaseibacillus rhamnosusLung NeoplasmsProbioticsAnimalsCarcinogensDisease Models, AnimalHot TemperatureMiceTumor MicroenvironmentCarcinogensaerosolcarcinogenesisIgAJ chainLactobacillus rhamnosuslung cancerlung microbiotamouse modelstumor preventionurethane

Identifiers

PMID36361537
PMCPMC9656640
OpenAlexW4308119573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.