Evidence map›Paper›PMID 36361507›Full record

ArticleInternational journal of molecular sciences2022

Changes in Polychlorinated Biphenyl Residues in Milk during Lactation: Levels of Contamination, Influencing Factors, and Infant Risk Assessment.

Agata Witczak, Anna Pohoryło, Aleksandra Aftyka, Kamila Pokorska-Niewiada, Grzegorz Witczak

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Identification of nanoparticle infiltration in human breast milk: Chemical profiles and trajectory pathways.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Agata WitczakDepartment of Toxicology, Dairy Technology, and Food Storage, West Pomeranian University of Technology in Szczecin, Papieża Pawła VI Street 3, 71-459 Szczecin, Poland.ORCID 0000-0002-7705-2138
Anna PohoryłoDepartment of Toxicology, Dairy Technology, and Food Storage, West Pomeranian University of Technology in Szczecin, Papieża Pawła VI Street 3, 71-459 Szczecin, Poland.
Aleksandra AftykaVeterinary Inspection Provincial Veterinary Inspectorate in Szczecin, 71-337 Szczecin, Poland.
Kamila Pokorska-NiewiadaDepartment of Toxicology, Dairy Technology, and Food Storage, West Pomeranian University of Technology in Szczecin, Papieża Pawła VI Street 3, 71-459 Szczecin, Poland.ORCID 0000-0002-4835-8517
Grzegorz WitczakDepartment of Gynecology, Endocrinology and Gynecological Oncology, Pomeranian Medical University in Szczecin, 71-252 Szczecin, Poland.ORCID 0000-0002-2016-6812
West Pomeranian University of Technology in Szczecin · PLChief Inspectorate of Environmental Protection · PLPomeranian Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the importance of breastfeeding infants, the contamination of human milk is a significant public concern. The aim of this study was to assess the contamination of human milk with dioxin-like PCBs (dl-PCBs) and non-dioxin-like PCBs (ndl-PCBs) in relation to the duration of lactation and other influencing factors, especially the frequency of the consumption of selected foods during pregnancy. Based on this, the health risk to infants was assessed and compared to the tolerable daily intake (TDI). PCB determinations were performed using gas chromatography/mass spectrometry. The ∑ndl-PCB content ranged from 0.008 to 0.897 ng/g w.w., at an average of 0.552 ng/g wet weight, which was 55% of the maximum level according to the EU guidelines for foods for infants and young children. The toxic equivalent (TEQ) was in the range of 0.033-5.67 pg-TEQ/g w.w. The content of non-ortho, mono-ortho, and ndl-PCBs in human milk decreased the longer lactation continued. Moreover, when pregnant women smoked tobacco, this correlated significantly with increases in the concentrations of PCB congeners 156, 118, and 189 in human milk. The human milk contents of PCB congeners 77, 81, 186, 118, and 189 were strongly positively correlated with the amount of fish consumed. The content of stable congeners PCB 135 and PCB 153 increased with age.

Indexed as

BenzofuransDioxinsPolychlorinated BiphenylsPolychlorinated DibenzodioxinsAnimalsBreast FeedingChildChild, PreschoolFemaleFood ContaminationHumansInfantLactationMilk, HumanPregnancyRisk Assessment2,3,3',4,4',5-hexachlorobiphenyl3,4,3',4'-tetrachlorobiphenylBenzofuransDioxinsPolychlorinated BiphenylsPolychlorinated Dibenzodioxinshuman milkinfant healthpolychlorinated biphenylsstages of lactation

Identifiers

PMID36361507
PMCPMC9655485
OpenAlexW4307263060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.