Evidence map›Paper›PMID 36361481›Full record

ArticleInternational journal of environmental research and public health2022

The Effects of Paroxetine on Benthic Microbial Food Web and Nitrogen Transformation in River Sediments.

Yi Li, Xinqi Chen, Xinzi Wang, Jiahui Shang, Lihua Niu, Longfei Wang, Huanjun Zhang, Wenlong Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yi LiKey Laboratory of Integrated Regulation and Resource Development of Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China.
Xinqi ChenKey Laboratory of Integrated Regulation and Resource Development of Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China.
Xinzi WangKey Laboratory of Integrated Regulation and Resource Development of Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China.
Jiahui ShangKey Laboratory of Integrated Regulation and Resource Development of Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China.
Lihua NiuKey Laboratory of Integrated Regulation and Resource Development of Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China.
Longfei WangKey Laboratory of Integrated Regulation and Resource Development of Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China.
Huanjun ZhangKey Laboratory of Integrated Regulation and Resource Development of Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China.
Wenlong ZhangKey Laboratory of Integrated Regulation and Resource Development of Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China.
Hohai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paroxetine is a common pharmaceutical to treat depression and has been found to pose threats to aquatic organisms. However, little is known about the effects of paroxetine on the nutrient cycle in aquatic environments. Therefore, DNA metabarcoding is used in this study to analyze the effects of paroxetine on multi-trophic microorganisms and nitrogen transformation in river sediments. Although paroxetine has no significant effect on the diversity of microbenthos, changes in benthic nitrogen-converting bacteria are consistent with the change in the various forms of nitrogen in the sediment, indicating that paroxetine affects the nitrogen conversion process by affecting nitrogen-converting bacteria. In addition, it is found that paroxetine has the ability to influence nitrogen transformation in an indirect way by affecting the trophic transfer efficiency of higher trophic levels (meiofauna and protozoa, protozoa and protozoa), subsequently affecting the growth of nitrogen-converting bacteria through a top-down mechanism (i.e., predation).The results show that paroxetine affects nitrogen transformation directly by affecting nitrogen-converting bacteria and indirectly through top-down effects, emphasizing that the assessment of paroxetine's ecological risks should consider species within different trophic levels.

Indexed as

Food ChainRiversAquatic OrganismsBacteriaEcosystemGeologic SedimentsNitrogenParoxetineNitrogenParoxetineDNA metabarcodingmicrobenthic communitiesmicrobial food webnitrogenparoxetine

Identifiers

PMID36361481
PMCPMC9657768
OpenAlexW4308522708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.