Evidence map›Paper›PMID 36361209›Full record

ArticleInternational journal of environmental research and public health2022

Computer-Assisted Annotation of Digital H&E/SOX10 Dual Stains Generates High-Performing Convolutional Neural Network for Calculating Tumor Burden in H&E-Stained Cutaneous Melanoma.

Patricia Switten Nielsen, Jeanette Baehr Georgsen, Mads Sloth Vinding, Lasse Riis Østergaard, Torben Steiniche

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Patricia Switten NielsenDepartment of Pathology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 35, DK-8200 Aarhus, Denmark.ORCID 0000-0002-7859-6321
Jeanette Baehr GeorgsenDepartment of Pathology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 35, DK-8200 Aarhus, Denmark.ORCID 0000-0002-9452-2920
Mads Sloth VindingDepartment of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 82, DK-8200 Aarhus, Denmark.ORCID 0000-0002-0149-583X
Lasse Riis ØstergaardDepartment of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 7E, DK-9220 Aalborg, Denmark.
Torben SteinicheDepartment of Pathology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 35, DK-8200 Aarhus, Denmark.
Aarhus University · DKAalborg University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep learning for the analysis of H&E stains requires a large annotated training set. This may form a labor-intensive task involving highly skilled pathologists. We aimed to optimize and evaluate computer-assisted annotation based on digital dual stains of the same tissue section. H&E stains of primary and metastatic melanoma (

Indexed as

MelanomaSkin NeoplasmsComputersCutaneous Malignant MelanomaHumansNeural Networks, ComputerSOXE Transcription FactorsTumor BurdenSOX10 protein, humanSOXE Transcription Factorsartificial intelligencedeep learningdigital multiple stainsdigital pathologyH&EIHC-supervised annotationimmunohistochemistrymelanomaSOX10tumor burden

Identifiers

PMID36361209
PMCPMC9654525
OpenAlexW4308106582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.