ReviewInternational journal of environmental research and public health2022
Wildfire Smoke Exposure during Pregnancy: A Review of Potential Mechanisms of Placental Toxicity, Impact on Obstetric Outcomes, and Strategies to Reduce Exposure.
Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Systematic review of climate change interventions for improving child health.BMJ paediatrics open · 2026Pooled it
- Risks to the Unborn: An Umbrella Review on the Effects of Prenatal Maternal Stress Caused by Natural Disasters.Stress and health : journal of the International Society for the Investigation of Stress · 2025Pooled it
- Prenatal exposure to wildfire fine particulate matter and fetal growth outcomes in the United States: Findings from the ECHO Cohort.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Wildland fire smoke, severe maternal morbidity, and health equity: A population-based cohort study in California.The Science of the total environment · 2026Article
- Narrative review of wildfire smoke interventions: considering the unique vulnerabilities of children and pregnant individuals.Journal of exposure science & environmental epidemiology · 2026Review
- Exposure metrics for smoke waves from wildland fires and their associations with preterm birth in California.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- The Effect of Wildfire Exposure: Neurological Outcomes, Mental Health, and Epigenetic Insights.Genes · 2026Review
- Gestational fine particulate matter exposure and perinatal outcomes in the ECHO cohort: Associations across pregnancy windows.Environmental research · 2026Article
- Prenatal exposure to wildfire-related PMEnvironment international · 2026Article
- Impact of Wildland Fire Smoke PMEnvironmental science & technology · 2026Article
- Climate Change and Reproductive Health.Endocrine reviews · 2025Review
- Exposure to Fine Particulate Matter During Pregnancy Is Associated With Hippocampal Development in Offspring.Biological psychiatry global open science · 2025Article
- Adverse Birth Outcomes Associated with Heat Stress and Wildfire Smoke Exposure During Preconception and Pregnancy.Environmental science & technology · 2025Article
- Conceptual GeoHealth Framework for Disaster Response Research: Case Study for Wildland Urban Interface (WUI) Fires and Data Integration.GeoHealth · 2025Article
- Quantifying the association between pregnancy exposure to biomass-attributable PMEnvironmental epidemiology (Philadelphia, Pa.) · 2025Article
- The Camp fire and perinatal health: an example of the generalized synthetic control method to identify susceptible windows of exposure.American journal of epidemiology · 2025Article
- Insights into the Global and Mexican Context of Placental-Derived Pregnancy Complications.Biomedicines · 2025Review
- Perceptions of and Responses to Wildfire Smoke Among New York State Residents: A Cross-Sectional Study.International journal of environmental research and public health · 2025Article
- Behavioral Responses to Wildfire Smoke: A Case Study in Western Montana.Journal of community health · 2025Article
- Scoping review of climate drivers on maternal health: current evidence and clinical implications.AJOG global reports · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Climate change is accelerating the intensity and frequency of wildfires globally. Understanding how wildfire smoke (WS) may lead to adverse pregnancy outcomes and alterations in placental function via biological mechanisms is critical to mitigate the harms of exposure. We aim to review the literature surrounding WS, placental biology, biological mechanisms underlying adverse pregnancy outcomes as well as interventions and strategies to avoid WS exposure in pregnancy. This review includes epidemiologic and experimental laboratory-based studies of WS, air pollution, particulate matter (PM), and other chemicals related to combustion in relation to obstetric outcomes and placental biology. We summarized the available clinical, animal, and placental studies with WS and other combustion products such as tobacco, diesel, and wood smoke. Additionally, we reviewed current recommendations for prevention of WS exposure. We found that there is limited data specific to WS; however, studies on air pollution and other combustion sources suggest a link to inflammation, oxidative stress, endocrine disruption, DNA damage, telomere shortening, epigenetic changes, as well as metabolic, vascular, and endothelial dysregulation in the maternal-fetal unit. These alterations in placental biology contribute to adverse obstetric outcomes that disproportionally affect the most vulnerable. Limiting time outdoors, wearing N95 respirator face masks and using high quality indoor air filters during wildfire events reduces exposure to related environmental exposures and may mitigate morbidities attributable to WS.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.