Evidence map›Paper›PMID 36360496›Full record

ArticleHealthcare (Basel, Switzerland)2022

Heterogeneity in Response to MCT and Psychoeducation: A Feasibility Study Using Latent Class Mixed Models in First-Episode Psychosis.

Marta Ferrer-Quintero, Daniel Fernández, Raquel López-Carrilero, Luciana Díaz-Cutraro, Marina Verdaguer-Rodríguez, Helena García-Mieres, Elena Huerta-Ramos, Juana Gómez-Benito, Trini Peláez, Irene Birulés and 10 more

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Efficacy of metacognitive therapies in first-episode psychosis: a systematic review.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2026
    Article
  2. Efficacy of metacognitive therapies in first-episode psychosis: a systematic review.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Marta Ferrer-QuinteroParc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain.ORCID 0000-0002-7935-9424
Daniel FernándezCentro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0003-0012-2094
Raquel López-CarrileroParc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain.ORCID 0000-0003-4110-794X
Luciana Díaz-CutraroParc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain.ORCID 0000-0003-3985-2780
Marina Verdaguer-RodríguezParc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain.ORCID 0000-0001-9910-1220
Helena García-MieresHealth Services Research Group, Instituto Hospital del Mar de Investigaciones Médicas, 08003 Barcelona, Spain.ORCID 0000-0002-2813-1737
Elena Huerta-RamosParc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain.
Juana Gómez-BenitoDepartment of Social and Quantitative Psychology, Faculty of Psychology, University of Barcelona, 08035 Barcelona, Spain.ORCID 0000-0002-4280-3106
Trini PeláezParc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain.
Irene BirulésParc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain.ORCID 0000-0001-6518-7310
Ana BarajasSerra Húnter Fellow Departament de Psicologia Clínica i de la Salut, Facultat de Psicologia, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.ORCID 0000-0003-1103-9499
Esther PousaCentro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0003-4423-6739
Marisa BarrigónDepartament of Psychiatry, University Hospital Virgen del Rocio, 41013 Seville, Spain.ORCID 0000-0002-2497-6353
Alfonso Gutiérrez-ZotesCentro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain.
Eva GrasaCentro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0003-1100-7489
Isabel Ruiz-DelgadoUnidad de Salud Mental Comunitaria Malaga Norte, 29014 Málaga, Spain.
Esther Lorente-RoviraCentro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain.
Jordi CidMental Health & Addiction Research Group, IdiBGi, Institut d'Assistencia Sanitària, 17190 Girona, Spain.ORCID 0000-0002-6406-0585
On Behalf Of The Spanish Metacognition Study Group
Susana OchoaParc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain.ORCID 0000-0001-6792-1080

Funding

Andalusian Regional Ministry of Health PI-0634/2011 and PI-0193/2014Instituto de Salud Carlos III PI11/01347, PI14/00044 and PI18/00212La Caixa Recercaixa 2013Obra Social Sant Joan de Déu, BML RTI2018-100927-J-I00Royal Marsden NHS Foundation Trust E2987-3648
6 · The paper itself

Abstract

Metacognitive training (MCT) is an effective treatment for psychosis. Longitudinal trajectories of treatment response are unknown but could point to strategies to maximize treatment efficacy during the first episodes. This work aims to explore the possible benefit of using latent class mixed models (LCMMs) to understand how treatment response differs between metacognitive training and psychoeducation. We conducted LCMMs in 28 patients that received MCT and 34 patients that received psychoeducation. We found that MCT is effective in improving cognitive insight in all patients but that these effects wane at follow-up. In contrast, psychoeducation does not improve cognitive insight, and may increase self-certainty in a group of patients. These results suggest that LCMMs are valuable tools that can aid in treatment prescription and in predicting response to specific treatments.

Indexed as

first-episode psychosislatent class mixed modelsmetacognitionmetacognitive trainingpsychoeducationsocial cognition

Identifiers

PMID36360496
PMCPMC9691095

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.