Evidence map›Paper›PMID 36360427›Full record

ReviewChildren (Basel, Switzerland)2022

Long-Term Ventilation in Children with Medical Complexity: A Challenging Issue.

Valeria Caldarelli, Federica Porcaro, Paola Di Filippo, Marina Attanasi, Valentina Fainardi, Marcella Gallucci, Angelo Mazza, Nicola Ullmann, Stefania La Grutta

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Valeria CaldarelliDepartment of Mother and Child, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
Federica PorcaroPediatric Pulmonology & Respiratory Intermediate Care Unit, Sleep and Long-Term Ventilation Unit, Academic Department of Pediatrics, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.ORCID 0000-0001-7779-728X
Paola Di FilippoDepartment of Pediatrics, SS Annunziata Hospital, University of Chieti, 66100 Chieti, Italy.
Marina AttanasiDepartment of Pediatrics, SS Annunziata Hospital, University of Chieti, 66100 Chieti, Italy.
Valentina FainardiCystic Fibrosis Unit, Department of Paediatrics, Parma University Hospital, 43126 Parma, Italy.
Marcella GallucciDepartment of Pediatrics, S. Orsola-Malpighi Hospital, University of Bologna, 40126 Bologna, Italy.
Angelo MazzaDepartment of Pediatrics, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy.ORCID 0000-0002-3976-5495
Nicola UllmannPediatric Pulmonology & Respiratory Intermediate Care Unit, Sleep and Long-Term Ventilation Unit, Academic Department of Pediatrics, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Stefania La GruttaInstitute of Traslational Pharmacology IFT, National Research Council, 90146 Palermo, Italy.ORCID 0000-0001-8026-0715

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children with medical complexity (CMCs) represent a subgroup of children who may have congenital or acquired multisystemic disease. CMCs are frequently predisposed to respiratory problems and often require long-term mechanical ventilation (LTMV). The indications for LTMV in CMCs are increasing, but gathering evidence about indications, titration, and monitoring is currently the most difficult challenge due to the absence of validated data. The aim of this review was to examine the clinical indications and ethical considerations for the initiation, continuation, or withdrawal of LTMV among CMCs. The decision to initiate long-term ventilation should always be based on clinical and ethical considerations and should be shared with the parents.

Indexed as

children with medical complexitycontinuous positive airway pressureethical issueslong-term invasive mechanical ventilationpalliative caresleep apnea syndromesleep-disordered breathing

Identifiers

PMID36360427
PMCPMC9688784

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.