ReviewChildren (Basel, Switzerland)2022
Evaluation and Treatment of Pain in Fetuses, Neonates and Children.
Review in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Effect of stress-ball play on pain and physiological responses during port-a-cath needle insertion in children undergoing chemotherapy: a randomized controlled trial.BMC pediatrics · 2026Trial
- A Multi-Center Evaluation of the Pharmacokinetics and Safety of Intravenous Ibuprofen in Infants 1-6 Months of Age.Paediatric drugs · 2023Trial
- Local anesthetic techniques for analgesia in neonatal circumcision: a network meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Effectiveness of Sucrose Versus Breast Milk as Non-Pharmacological Measures in the Management of Neonatal Pain: A Systematic Review.Children (Basel, Switzerland) · 2026Review
- Enhancing neonatal vascular access: proposing a patient-centered framework based on 7-Rights.Pediatric research · 2026Article
- How Often Are Hospitalised Children Physically Restrained During Painful and Stressful Procedures?Journal of clinical nursing · 2026Observational
- Pharmacological therapy of neonatal analgosedation: current status, dilemmas, and perspectives.Frontiers in pediatrics · 2026Review
- Chemical stability and compatibility of acetaminophen injection with six common opioid drugs: implications for clinical use.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026Article
- Key factors influencing children's cooperation during electromyography: a correlation analysis of Age, gender, and pain management.Frontiers in pediatrics · 2026Article
- Paediatric Fever Management Practices and Antipyretic Use Among Doctors and Nurses in Australian Emergency Departments.Emergency medicine Australasia : EMA · 2025Article
- Review
- Paediatric Pain Management Experiences of Parents of Children in Botswana Referral Hospitals.Nursing open · 2025Article
- The Impact of Surgical Repair on Restlessness in Infants with Non-Incarcerated Inguinal Hernias: A Prospective Study.Journal of clinical medicine · 2025Article
- ERCP-Related adverse events in pediatric patients: a 10-years single-site review.Pediatric surgery international · 2024Article
- Long-term effects of neonatal pain and sucrose treatment.Current research in pharmacology and drug discovery · 2024Article
- Pain Management in Children Admitted to the Emergency Room: A Narrative Review.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Magnesium Sulfate in Pediatric Abdominal Cancer Surgery: Safety and Efficacy in Ultrasound-Guided Transversus Abdominis Plane (US-TAP) Block in Conjugation with Levobupivacaine.Local and regional anesthesia · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The perception of pain is individual and differs between children and adults. The structures required to feel pain are developed at 24 weeks of gestation. However, pain assessment is complicated, especially in neonates, infants and preschool-age children. Clinical scales adapted to age are the most used methods for assessing and monitoring the degree of pain in children. They evaluate several behavioral and/or physiological parameters related to pain. Some monitors detect the physiological changes that occur in association with painful stimuli, but they do not yet have a clear clinical use. Multimodal analgesia is recommended for pain treatment with non-pharmacological and pharmacological interventions. It is necessary to establish pharmacotherapeutic protocols for analgesia adjusted to the acute or chronic, type and intensity of pain, as well as age. The most used analgesics in children are paracetamol, ibuprofen, dipyrone, opioids (morphine and fentanyl) and local anesthetics. Patient-controlled analgesia is an adequate alternative for adolescent and older children in specific situations, such as after surgery. In patients with severe or persistent pain, it is very important to consult with specific pain services.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.