Evidence map›Paper›PMID 36360381›Full record

ArticleChildren (Basel, Switzerland)2022

Severe Neurological Manifestation in a Child with Multisystem Inflammatory Syndrome.

Mônica de Oliveira Santos, Diuly Caroline Ribeiro, Jordanna Sousa Rocha, Sibely Braga Santos Maia, André Luís Elias Moreira, Paulo Alex Neves Silva, Célia Regina Malveste Ito, Lilian Carla Carneiro, Melissa Ameloti Gomes Avelino

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PubMed Full text at PMC Publisher
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mônica de Oliveira SantosClinical Pathology and Medicine, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.
Diuly Caroline RibeiroDepartment of Pediatrics, Hospital das Clinicas, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.
Jordanna Sousa RochaDepartment of Pediatrics, Hospital das Clinicas, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.
Sibely Braga Santos MaiaDepartment of Pediatrics, Hospital Estadual de Doenças Tropicais, Goiânia 74850-400, GO, Brazil.
André Luís Elias MoreiraClinical Pathology and Medicine, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.
Paulo Alex Neves SilvaDepartment of Microbiology, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.
Célia Regina Malveste ItoDepartment of Microbiology, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.
Lilian Carla CarneiroDepartment of Microbiology, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.
Melissa Ameloti Gomes AvelinoDepartment of Pediatrics, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.ORCID 0000-0003-0342-0978
Universidade Federal de Goiás · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 0678/2020 /88881.504906/2020-01
6 · The paper itself

Abstract

BACKGROUND AND

objectivesDuring the COVID-19 pandemic, we followed with concern the evolution of several children diagnosed with Multisystem Inflammatory Syndrome in Children (MIS-C). The purpose of this study is to describe the evolution of MIS-C in a previously healthy 3-year-old girl.

methodsWe tracked the daily medical report of all children admitted with suspected MIS-C to the five largest regional hospitals.

resultsOur screening identified a child who had several neurological complications associated with MIS-C. We report hematological alterations, transient cardiac dysfunction, and cerebral involvements such as laminar cortical necrosis caused by ischemic stroke. We present the course of treatment and clinical outcome, and other complications such as a severe subglottic stenosis occurring after extubation.

conclusionSubglottic stenosis is an expected complication after prolonged intubation, and the presence of dysphonia and/or stridor is an important predictive factor. MIS-C with severe neurological alteration may occur in a healthy child, and early diagnosis and treatment with a pulse of corticoid with immunoglobulin are essential for a favorable outcome.

Indexed as

childrenischemic strokeSARS-CoV-2

Identifiers

PMID36360381
PMCPMC9688372
OpenAlexW4307946489

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.