Evidence map›Paper›PMID 36360355›Full record

ArticleChildren (Basel, Switzerland)2022

Atrioventricular Block in Celiac Disease: An Unusual Clinical Presentation in a Child. A Case-Based Review.

Savina Mannarino, Sara Santacesaria, Irene Raso, Giulia Fini, Elena Pozzi, Cristina Cocuccio, Valeria Calcaterra, Gianvincenzo Zuccotti

Open access · goldAbstract readCase Reports
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. The heart of celiac disease: understanding dilated cardiomyopathy, pathophysiology, and care-a systematic review.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024
    Review
  3. Cardiomyopathy in Celiac Disease: A Systematic Review.Journal of clinical medicine · 2024
    Review
  4. Celiac Disease and the Risk of Cardiovascular Diseases.International journal of molecular sciences · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Savina MannarinoPediatric Cardiology Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.
Sara SantacesariaPediatric Cardiology Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.
Irene RasoPediatric Cardiology Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.
Giulia FiniPediatric Cardiology Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.
Elena PozziPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.
Cristina CocuccioPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.
Valeria CalcaterraPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.ORCID 0000-0002-2137-5974
Gianvincenzo ZuccottiPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.ORCID 0000-0002-2795-9874
Ospedale dei Bambini Vittore Buzzi · ITUniversity of Milan · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital or acquired atrioventricular block (AVB) is a rare disorder in the pediatric population, while celiac disease (CeD) is a common multisystemic autoimmune disorder that is characterized by intestinal manifestations as they are the typical clinical presentation. Sometimes CeD presents more complex multisystemic involvement which includes the heart. Cardiac involvement, such as dilated cardiomyopathy, myocarditis or conduction disease, have been mainly described in untreated adult patients with or without gastro-intestinal symptoms; rare cases of AVB and CeD have been also reported, particularly in association with extra-cardiac manifestations. We describe a case of a progressive acquired AVB block in a 4-year-old child, in which CeD was later diagnosed. A rapid and significantly improvement of the AVB grade has been obtained after the child started a strict gluten-free diet, and so we suggest including diagnostic exams for CeD in all of the children with acquired AVB.

Indexed as

atrioventricular blockcardiac involvementceliac diseasechildrenconduction disorders

Identifiers

PMID36360355
PMCPMC9688162
OpenAlexW4307348961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.