Evidence map›Paper›PMID 36360284›Full record

ArticleGenes2022

Retinal Gene Expression of Selective Genes and Histological Stages of Embryonic and Post-Hatch Chickens (

Nasmah K Bastaki, Vanessa R Lobo, Thecla Gomes, Taybha A Albarjes

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Nasmah K BastakiDepartment of Biological Science, Faculty of Science, Kuwait University, Kuwait City 13060, Kuwait.ORCID 0000-0003-4394-0126
Vanessa R LoboDepartment of Bioinformatics and System Biology, University of Manchester, Manchester M13 9PL, UK.
Thecla GomesDepartment of Biological Science, Faculty of Science, Kuwait University, Kuwait City 13060, Kuwait.
Taybha A AlbarjesDepartment of Biological Science, Faculty of Science, Kuwait University, Kuwait City 13060, Kuwait.
Kuwait University · KWUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chickens are excellent models for the study of retinal development and function. Gene expression at the correct time is crucial to retinal development and function. The present study aimed to investigate retinal gene expression and morphology in locally grown chickens at various developmental stages. RNA was extracted from the retina at the embryonic and post-hatch stages, and the retinal layers were stained with haematoxylin and eosin (H&E). RT-PCR and RT-qPCR were used for gene expression analysis of 14 selected genes. The results showed that all the retinal genes were expressed at different developmental stages. However, there were slight noticeable variations in expression patterns. At the morphological level, all retinal layers were well observed, except for the outer plexiform layer that became visible in the fifteen-day chick embryo. The current study provides a baseline for standard retinal gene expression of 14 genes and retinal histological staining. The selected genes have different roles in retinal development and function, and most of these genes are associated with retinal diseases. The results obtained here can be applied to molecular retinal research and retinal diseases with genetic factors in retina animal models or human diseases.

Indexed as

ChickensRetinal DiseasesAnimalsChick EmbryoGene ExpressionGene Expression Regulation, DevelopmentalHumansRetinaadult chickenembryonic chickgene expressionhistology stainingretina

Identifiers

PMID36360284
PMCPMC9690827
OpenAlexW4308531338

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.