Evidence map›Paper›PMID 36360268›Full record

ArticleGenes2022

Racial Disparities in Methylation of

Priyadarshni Patel, Vaithinathan Selvaraju, Jeganathan Ramesh Babu, Xu Wang, Thangiah Geetha

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Priyadarshni PatelDepartment of Nutritional Sciences, Auburn University, Auburn, AL 36849, USA.
Vaithinathan SelvarajuDepartment of Nutritional Sciences, Auburn University, Auburn, AL 36849, USA.
Jeganathan Ramesh BabuDepartment of Nutritional Sciences, Auburn University, Auburn, AL 36849, USA.
Xu WangAlabama Agricultural Experiment Station, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0002-7594-5004
Thangiah GeethaDepartment of Nutritional Sciences, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0001-6358-0012
Auburn University · USHudsonAlpha Institute for Biotechnology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood obesity has affected the health of millions of children around the world despite vigorous efforts by health experts. The obesity epidemic in the United States has disproportionately afflicted certain racial and ethnic minority groups. African American children are more likely than other children to have obesity-related risk factors such as hyperlipidemia, diabetes, cardiovascular disease, and coronavirus disease (COVID-19). For the reduction in obesity-related health inequalities to be successful, it is essential to identify the variables affecting various groups. A notable advancement in epigenetic biology has been made over the past decade. Epigenetic changes like DNA methylation impact on many genes associated with obesity. Here, we evaluated the DNA methylation levels of the genes

Indexed as

COVID-19Pediatric ObesityAlpha-Ketoglutarate-Dependent Dioxygenase FTOChildEthnicityHumansMinority GroupsNuclear Respiratory Factor 1OverweightReceptors, LeptinUnited StatesAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humanLEPR protein, humanNRF1 protein, humanNuclear Respiratory Factor 1Receptors, Leptinchildhood obesityDNA methylationepigeneticsFTOhealth disparitiesLEPRNRF1

Identifiers

PMID36360268
PMCPMC9690504
OpenAlexW4308207129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.