Evidence map›Paper›PMID 36360261›Full record

ArticleGenes2022

Balancing at the Borderline of a Breed: A Case Study of the Hungarian Short-Haired Vizsla Dog Breed, Definition of the Breed Profile Using Simple SNP-Based Methods.

László Varga, Erika Meleg Edviné, Péter Hudák, István Anton, Nóra Pálinkás-Bodzsár, Attila Zsolnai

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

László VargaInstitute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent István Campus, 2100 Gödöllő, Hungary.ORCID 0000-0001-9039-2578
Erika Meleg EdvinéInstitute for Farm Animal Gene Conservation, National Centre for Biodiversity and Gene Conservation, 2100 Gödöllő, Hungary.
Péter HudákInstitute for Farm Animal Gene Conservation, National Centre for Biodiversity and Gene Conservation, 2100 Gödöllő, Hungary.
István AntonDepartment of Animal Breeding, Institute of Animal Science, Hungarian University of Agriculture and Life Sciences, Kaposvár Campus, 2053 Herceghalom, Hungary.ORCID 0000-0001-8099-6992
Nóra Pálinkás-BodzsárInstitute for Farm Animal Gene Conservation, National Centre for Biodiversity and Gene Conservation, 2100 Gödöllő, Hungary.
Attila ZsolnaiInstitute for Farm Animal Gene Conservation, National Centre for Biodiversity and Gene Conservation, 2100 Gödöllő, Hungary.ORCID 0000-0002-8382-1503
Magyar Agrár- és Élettudományi Egyetem · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to determine the breed boundary of the Hungarian Short-haired Vizsla (HSV) dog breed. Seventy registered purebred HSV dogs were genotyped on approximately 145,000 SNPs. Principal Component Analysis (PCA) and Admixture analysis certified that they belong to the same population. The outer point of the breed demarcation was a single Hungarian Wire-haired Vizsla (HWV) individual, which was the closest animal genetically to the HSV population in the PCA analysis. Three programs were used for the breed assignment calculations, including the widely used GeneClass2.0 software and two additional approaches developed here: the 'PCA-distance' and 'IBS-central' methods. Both new methods calculate a single number that represents how closely a dog fits into the actual reference population. The former approach calculates this number based on the PCA distances from the median of HSV animals. The latter calculates it from identity by state (IBS) data, measuring the distance from a central animal that is the best representative of the breed. Having no mixed-breed dogs with known HSV genome proportion, admixture animals were simulated by using data of HSV and HWV individuals to calibrate the inclusion/exclusion probabilities for the assignment. The numbers generated from these relatively simple calculations can be used by breeders and clubs to keep their populations under genetic supervision.

Indexed as

DogsPolymorphism, Single NucleotideAnimalsGenomeGenotypeHungarybreed assignmentHungarian Short-haired VizslaIBS-centralPCA-distanceSNP-chip

Identifiers

PMID36360261
PMCPMC9690546
OpenAlexW4308333772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.