Evidence map›Paper›PMID 36360201›Full record

ReviewGenes2022

Potential Mechanisms of Gut-Derived Extracellular Vesicle Participation in Glucose and Lipid Homeostasis.

Tiange Feng, Weizhen Zhang, Ziru Li

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Tiange FengDepartment of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100191, China.ORCID 0000-0003-4642-9905
Weizhen ZhangDepartment of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100191, China.
Ziru LiMaineHealth Institute for Research, MaineHealth, Scarborough, ME 04074, USA.
Peking University · CNMaineHealth · US

Funding

The role of night shift work in metabolic disorders during and after pregnancyP20GM121301 · NIGMS · MAINEHEALTH · PI Lucy Liaw · 2017 to 2026
$25.1M
The mTOR-ETV5 signaling in gastric X/A like cells and its role in hepatic lipid metabolism and steatosisR01DK129360 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEELEY, RANDY J · 2021 to 2024
$2.4M
R-spondin1-LGR4 Signaling and Ischemia/Reperfusion Injury in Steatotic LiverR01DK110273 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MULHOLLAND, MICHAEL W., ZHANG, WEIZHEN · 2017 to 2021
$2.1M
Gastric X/A Like Cells in Health and DiseasesR01DK112755 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEELEY, RANDY J · 2018 to 2022
$1.6M
NIDDK NIH HHS R01 DK110273NIDDK NIH HHS R01 DK112755NIDDK NIH HHS R01 DK129360NIGMS NIH HHS P20 GM121301
6 · The paper itself

Abstract

The intestine participates in the regulation of glucose and lipid metabolism in multiple facets. It is the major site of nutrient digestion and absorption, provides the interface as well as docking locus for gut microbiota, and harbors hormone-producing cells scattered throughout the gut epithelium. Intestinal extracellular vesicles are known to influence the local immune response, whereas their roles in glucose and lipid homeostasis have barely been explored. Hence, this current review summarizes the latest knowledge of cargo substances detected in intestinal extracellular vesicles, and connects these molecules with the fine-tuning regulation of glucose and lipid metabolism in liver, muscle, pancreas, and adipose tissue.

Indexed as

Extracellular VesiclesGastrointestinal MicrobiomeGlucoseHomeostasisLipidsGlucoseLipidsextracellular vesiclesglucose metabolismintestinelipid metabolismmicrobiota

Identifiers

PMID36360201
PMCPMC9689624
OpenAlexW4307942644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.