Evidence map›Paper›PMID 36360023›Full record

ReviewFoods (Basel, Switzerland)2022

Towards Substitution of Hexane as Extraction Solvent of Food Products and Ingredients with No Regrets.

Christian Cravotto, Anne-Sylvie Fabiano-Tixier, Ombéline Claux, Maryline Abert-Vian, Silvia Tabasso, Giancarlo Cravotto, Farid Chemat

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
  2. WildFood science & nutrition · 2026
    Article
  3. Article
  4. Potency ofThe Kobe journal of medical sciences · 2026
    Article
  5. Article
  6. Article
  7. Structural and functional properties ofFood production, processing and nutrition · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Prospects in the Use ofBiotech (Basel (Switzerland)) · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Christian CravottoGREEN Extraction Team, INRAE, UMR 408, Avignon University, F-84000 Avignon, France.ORCID 0000-0001-8382-3640
Anne-Sylvie Fabiano-TixierGREEN Extraction Team, INRAE, UMR 408, Avignon University, F-84000 Avignon, France.
Ombéline ClauxGREEN Extraction Team, INRAE, UMR 408, Avignon University, F-84000 Avignon, France.
Maryline Abert-VianGREEN Extraction Team, INRAE, UMR 408, Avignon University, F-84000 Avignon, France.ORCID 0000-0002-3306-1403
Silvia TabassoDepartment of Drug Science and Technology, University of Turin, Via P. Giuria 9, 10125 Turin, Italy.ORCID 0000-0002-1567-8143
Giancarlo CravottoDepartment of Drug Science and Technology, University of Turin, Via P. Giuria 9, 10125 Turin, Italy.ORCID 0000-0001-7574-7350
Farid ChematGREEN Extraction Team, INRAE, UMR 408, Avignon University, F-84000 Avignon, France.ORCID 0000-0002-1712-3969
Université d'Avignon et des Pays de Vaucluse · FRUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hexane is a solvent used extensively in the food industry for the extraction of various products such as vegetable oils, fats, flavours, fragrances, colour additives or other bioactive ingredients. As it is classified as a "processing aid", it does not have to be declared on the label under current legislation. Therefore, although traces of hexane may be found in final products, especially in processed products, its presence is not known to consumers. However, hexane, and in particular the

Indexed as

2,5-hexanedionealternative extraction methodsfood industryhexanetoxicity

Identifiers

PMID36360023
PMCPMC9655691
OpenAlexW4307941473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.