ReviewFoods (Basel, Switzerland)2022
Oral Tolerance Induction-Opportunities and Mechanisms.
Review in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- Early-life animal and farming exposures and the risk of rheumatoid arthritis: findings from the E3N French cohort study.RMD open · 2025Trial
- Allergen Sensitization Profiles and Co-Sensitization Networks in Children with Allergic Rhinitis and Asthma: A Propensity Score-Matched Retrospective Study.Journal of asthma and allergy · 2026Article
- Allergens in Atopic Dermatitis.Clinical reviews in allergy & immunology · 2025Review
- Worldwide Heterogeneity of Food Allergy: Focus on Peach Allergy in Southern Italy.Journal of clinical medicine · 2024Review
- Nanosized Additives: Silicon Dioxide's Potential Role in Development of Food Sensitivities in Mice.Environmental health perspectives · 2024Article
- Metabolic alterations of the immune system in the pathogenesis of autoimmune diseases.PLoS biology · 2023Article
- Establishment of Food Allergy Model in Dextran Sulfate Sodium Induced Colitis Mice.Foods (Basel, Switzerland) · 2023Article
- Yeast oral vaccines against infectious diseases.Frontiers in microbiology · 2023Review
- Perspectives on Non-IgE-Mediated Gastrointestinal Food Allergy in Pediatrics: A Review of Current Evidence and Guidelines.Journal of asthma and allergy · 2023Review
- Disparities in Caregiver-Reported Knowledge, Attitudes, Behaviors, and Clinical Guidance Regarding Primary Prevention of Peanut Allergy.Academic pediatricsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Oral tolerance is the active absence of response to food allergens, which involves complex mechanisms in the gut-associated lymphoid tissue. Food allergy results from the disruption of such tolerance or the absence of its establishment in the first place. It follows allergic sensitization with the production of allergen-specific IgE and results from the degranulation of basophils and mast cells on subsequent exposure to the allergen. Oral tolerance induction has been explored in the contexts of prevention and treatment of food allergy. Early introduction of allergenic foods (i.e., egg and peanut) in the diet of infants, before allergic sensitization occurs (i.e., via inflamed skin affected with eczema) has shown to be beneficial. Guidelines have changed to recommend the introduction of these allergenic foods by 6 months of age. For food allergic individuals, oral tolerance induction has been attempted using allergen-specific immunotherapy, which involves the administration of an allergen, modified or not, through various possible routes, including oral, sublingual, epicutaneous, and subcutaneous, with or without concomitant administration of antibody-based biologics. Further research into the immune mechanisms of food allergy and oral tolerance can lead to the identification of novel targets to suppress the food allergic response and reverse the current food allergy epidemic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.