ArticleDiagnostics (Basel, Switzerland)2022
Nasal Mycology of Chronic Rhinosinusitis Revealed by Nanopore Sequencing.
Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
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- Hypertonic thermal solutions as a putative strategy for respiratory biofilm disruption.Open medicine (Warsaw, Poland) · 2026Article
- [The role ofLin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025Review
- Impact of Zinc Oxide on the Development ofCurrent issues in molecular biology · 2024Article
- Immunopathologic Role of Fungi in Chronic Rhinosinusitis.International journal of molecular sciences · 2023Review
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundNanopore sequencing (NS) is a third-generation sequencing technology capable of generating reads of long sequences. In this study, we used NS to investigate nasal mycology in patients with chronic rhinosinusitis (CRS).
methodsNasal cavities of 13 CRS patients were individually irrigated with 20 mL of distilled water. The irrigant was forcefully blown by the patient into a basin. The collected fluid was placed into a centrifuge tube and processed using the method of Ponikau et al. The collected specimens were used for traditional fungal culture and sequenced for total DNA using NS.
resultsTraditional fungal culture successfully grew fungi in the specimens of 11 (84.6%) patients.
conclusionOur results showed that NS was sensitive and fast in detecting nasal fungi in CRS patients.
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Registered trials
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