ArticleDiagnostics (Basel, Switzerland)2022
Angiomatoid Fibrous Histiocytoma (AFH) of the Right Arm: An Exceptional Case with Pulmonary Metastasis and Confirmatory EWSR1::CREB1 Translocation.
Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Angiomatoid fibrous histiocytoma: first report of adjacent venous invasion.Journal of surgical case reports · 2026Article
- A case of primary angiomatoid fibrous histiocytoma in the lung.Discover oncology · 2026Article
- Modeling Extraordinary Response Through Targeting Secondary Alterations in Fusion-Associated Sarcoma.JCO precision oncology · 2024Article
- Primary pulmonary myxoid sarcoma with EWSR1::CREB1 fusion: a literature review.Journal of cancer research and clinical oncology · 2024Review
- Difficulties in diagnosing angiomatoid fibrous histiocytoma of the head and neck region: A case report.World journal of clinical cases · 2023Article
- Pulmonary Metastasising Aneurysmal Fibrous Histiocytoma: A Case Report, Literature Review and Proposal of Standardised Diagnostic Criteria.Diseases (Basel, Switzerland) · 2023Article
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Authors and funding
13 authors at 3 institutions in 1 country.
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Abstract
Angiomatoid fibrous histiocytoma (AFH) is a rare neoplasm described for the first time by Enzinger in 1979, and classified by World Health Organization 2020 as intermediate malignant potential neoplasm. It mostly occurs in the subcutis and is characterized by varying proportions of epithelioid, ovoid and spindle cells in a nodular and syncytial growth pattern, with some hemorrhagic pseudovascular spaces. In this paper, we report the clinical case of a 62-year-old man who presented with AFH on the right arm, and relapsed three years after first surgical excision. After a further three years, the patient presented with an intramuscular localization of AFH, and 12 months after this, a pulmonary metastasis of AFH was diagnosed. Given the rarity of the spreading of AFH, we performed Fluorescence In Situ Hybridization (FISH) and we detected EWSR1::CREB1 gene fusion.
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