ArticleDiagnostics (Basel, Switzerland)2022
The Frequency and Causes of Not-Detected Breast Malignancy in Dynamic Contrast-Enhanced MRI.
Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Impact of background parenchymal enhancement on the diagnosis of enhancing lesions in breast MRI: a systematic approach.European radiology · 2026Article
- Article
- Factors associated with false-negative Kaiser score results in breast magnetic resonance imaging.Polish journal of radiology · 2026Article
- Development of uMUC-1 Targeted NEMO Particles with pH-Activatable MRI Signals for Enhanced Detection of Malignant Breast Cancer Cells.ACS applied bio materials · 2025Article
- Contrast-Enhanced Chest Computed Tomography forDiagnostics (Basel, Switzerland) · 2025Article
- Quantitative evaluation of Kaiser score in diagnosing breast dynamic contrast-enhanced magnetic resonance imaging for patients with high-grade background parenchymal enhancement.Quantitative imaging in medicine and surgery · 2023Article
- The Role of Diffusion-Weighted Imaging Based on Maximum-Intensity Projection in Young Patients with Marked Background Parenchymal Enhancement on Contrast-Enhanced Breast MRI.Life (Basel, Switzerland) · 2023Article
- Non-enhancing malignant lesions of the breast: A case report and review of literature.Heliyon · 2023Article
- Understanding Breast Cancer Aggressiveness and Its Implications in Diagnosis and Treatment.Journal of clinical medicine · 2023Article
- Diagnostic efficacy of ultrasound elastography and dynamic contrast-enhanced MR in benign and malignant breast masses.American journal of translational research · 2023Article
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5 authors.
Funding
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Abstract
Breast MR is the most sensitive imaging modality, but there are cases of malignant tumors that are not detected in MR. This study evaluated the frequency and main causes of malignant breast lesions not detected in dynamic contrast-enhanced (DCE) MR. A total of 1707 cases of preoperative breast MR performed between 2020 and 2021 were included. Three radiologists individually reviewed the DCE MRs and found not-detected malignancy cases in the MRs. The final cases were decided through consensus. For the selected cases, images other than DCE MRIs, such as mammography, ultrasounds, diffusion-weighted MRs, and, if possible, contrast-enhanced chest CTs, were analyzed. In the final sample, 12 cases were not detected in DCE MR, and the frequency was 0.7% (12/1707). Six cases were not detected due to known non-enhancing histologic features. In four cases, tumors were located in the breast periphery and showed no enhancement in MR. In the remaining two cases, malignant lesions were not identified due to underlying marked levels of BPE. The frequency of not-detected malignancy in DCE MR is rare. Knowing the causes of each case and correlating it with other imaging modalities could be helpful in the diagnosis of breast malignancy in DCE MR.
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