Evidence map›Paper›PMID 36359406›Full record

ArticleBiomedicines2022

The Efficacy of an N-Acetylcysteine-Antibiotic Combination Therapy on

Aditi Aiyer, Theerthankar Das, Gregory S Whiteley, Trevor Glasbey, Frederik H Kriel, Jessica Farrell, Jim Manos

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. The use of combination therapy for the improvement of colistin activity against bacterial biofilm.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Review
  3. Review
  4. Advances in the Use ofAntioxidants (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aditi AiyerCharles Perkins Centre, Infection, Immunity and Inflammation, Sydney Institute for Infectious Diseases, School of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia.
Theerthankar DasCharles Perkins Centre, Infection, Immunity and Inflammation, Sydney Institute for Infectious Diseases, School of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia.
Gregory S WhiteleyCharles Perkins Centre, Infection, Immunity and Inflammation, Sydney Institute for Infectious Diseases, School of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0001-7830-1725
Trevor GlasbeyWhiteley Corporation, 19-23 Laverick Avenue, Tomago, NSW 2322, Australia.
Frederik H KrielWhiteley Corporation, 19-23 Laverick Avenue, Tomago, NSW 2322, Australia.
Jessica FarrellCharles Perkins Centre, Infection, Immunity and Inflammation, Sydney Institute for Infectious Diseases, School of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia.
Jim ManosCharles Perkins Centre, Infection, Immunity and Inflammation, Sydney Institute for Infectious Diseases, School of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-5765-1563

Funding

This research was funded by COMMERCIAL DEVELOPMENT & INDUSTRY PARTNERSHIP, grant number CT20584-University of Sydney and Whiteley Corporation and DEPARTMENT OF IN-DUSTRY, INNOVATION AND SCIENCE (Innovative Manufacturing CRC Ltd.) and WHITELEY CORPORATION IMCRC/WLY/08052019.1 and CT20584
6 · The paper itself

Abstract

Cystic fibrosis (CF) is a disorder causing dysfunctional ion transport resulting in the accumulation of viscous mucus. This environment fosters a chronic bacterial biofilm-associated infection in the airways.

Indexed as

Achromobacter xylosoxidansartificial sputum mediumASMDM-1BEAS-2Bcell/Sputum modelcystic fibrosisN-acetylcysteine

Identifiers

PMID36359406
PMCPMC9687303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.