Evidence map›Paper›PMID 36359360›Full record

ArticleBiomedicines2022

Artificial Intelligence for Early Detection of Chest Nodules in X-ray Images.

Hwa-Yen Chiu, Rita Huan-Ting Peng, Yi-Chian Lin, Ting-Wei Wang, Ya-Xuan Yang, Ying-Ying Chen, Mei-Han Wu, Tsu-Hui Shiao, Heng-Sheng Chao, Yuh-Min Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Hwa-Yen ChiuDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0001-8759-7871
Rita Huan-Ting PengInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Yi-Chian LinInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Ting-Wei WangInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Ya-Xuan YangInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Ying-Ying ChenDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Mei-Han WuSchool of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Tsu-Hui ShiaoDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Heng-Sheng ChaoDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0002-0309-0983
Yuh-Min ChenDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0003-0585-8463
Yu-Te WuInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
National Yang Ming Chiao Tung University · TW

Funding

Ministry of Science and Technology MOST-108-3011-F-075-001Ministry of Science and Technology MOST111-2823-8-A49-001National Yang Ming Chiao Tung University Brain Research Center 111W32701
6 · The paper itself

Abstract

Early detection increases overall survival among patients with lung cancer. This study formulated a machine learning method that processes chest X-rays (CXRs) to detect lung cancer early. After we preprocessed our dataset using monochrome and brightness correction, we used different kinds of preprocessing methods to enhance image contrast and then used U-net to perform lung segmentation. We used 559 CXRs with a single lung nodule labeled by experts to train a You Only Look Once version 4 (YOLOv4) deep-learning architecture to detect lung nodules. In a testing dataset of 100 CXRs from patients at Taipei Veterans General Hospital and 154 CXRs from the Japanese Society of Radiological Technology dataset, the sensitivity of the AI model using a combination of different preprocessing methods performed the best at 79%, with 3.04 false positives per image. We then tested the AI by using 383 sets of CXRs obtained in the past 5 years prior to lung cancer diagnoses. The median time from detection to diagnosis for radiologists assisted with AI was 46 (3-523) days, longer than that for radiologists (8 (0-263) days). The AI model can assist radiologists in the early detection of lung nodules.

Indexed as

AIartificial intelligencedetectionlung cancermachine learning

Identifiers

PMID36359360
PMCPMC9687210
OpenAlexW4308531306

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.