Evidence map›Paper›PMID 36359353›Full record

ReviewBiomedicines2022

Cellular Prion Protein Role in Cancer Biology: Is It A Potential Therapeutic Target?

Saba Yousaf, Muhammad Ahmad, Siwen Wu, Muhammad Anjum Zia, Ishtiaq Ahmed, Hafiz M N Iqbal, Qingyou Liu, Saif Ur Rehman

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. PrPEnvironmental science & technology · 2026
    Article
  4. Article
  5. Integrated multi-omics elucidatesFrontiers in immunology · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Saba YousafState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources of Guangxi University, Nanning 530005, China.
Muhammad AhmadFaculty of Veterinary Sciences, Shaheed Benazir Bhutto University of Veterinary and Animal Sciences (SBBUVAS), Sakrand 67210, Pakistan.ORCID 0000-0003-3480-0615
Siwen WuState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources of Guangxi University, Nanning 530005, China.
Muhammad Anjum ZiaEnzyme Biotechnology Laboratory, Department of Biochemistry, University of Agriculture Faisalabad, Faisalabad 38040, Pakistan.
Ishtiaq AhmedDepartment of Regional Science Operations, La Trobe Rural Health School, Albury-Wodonga, VIC 3689, Australia.ORCID 0000-0003-3682-0812
Hafiz M N IqbalTecnologico de Monterrey, School of Engineering and Sciences, Monterrey 64849, Mexico.ORCID 0000-0003-4855-2720
Qingyou LiuState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources of Guangxi University, Nanning 530005, China.ORCID 0000-0003-3265-540X
Saif Ur RehmanState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources of Guangxi University, Nanning 530005, China.ORCID 0000-0002-5407-3112
Guangxi University · CNAlbury Wodonga Health · AUShaheed Benazir Bhutto University · PKTecnológico de Monterrey · MXUniversity of Faisalabad · PK

Funding

National Natural Science Foundation of China U20A2051
6 · The paper itself

Abstract

Cancers are worldwide health concerns, whether they are sporadic or hereditary. The fundamental mechanism that causes somatic or oncogenic mutations and ultimately aids cancer development is still unknown. However, mammalian cells with protein-only somatic inheritance may also contribute to cancerous malignancies. Emerging data from a recent study show that prion-like proteins and prions (PrP

Indexed as

cancer biologycancer cell drug resistanceEP/MAPK pathwayERK2 (MAPK1) pathwayprionprion proteinPRNPtherapeutic target

Identifiers

PMID36359353
PMCPMC9687521
OpenAlexW4308439070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.