Evidence map›Paper›PMID 36359330›Full record

ArticleBiomedicines2022

Inverse Salt Sensitivity of Blood Pressure Is Associated with an Increased Renin-Angiotensin System Activity.

John J Gildea, Peng Xu, Katie A Schiermeyer, Wei Yue, Robert M Carey, Pedro A Jose, Robin A Felder

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Anti-Inflammatory Effects of Peripheral Dopamine.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

John J GildeaDepartment of Pathology, The University of Virginia, Charlottesville, VA 22903, USA.
Peng XuDepartment of Pathology, The University of Virginia, Charlottesville, VA 22903, USA.
Katie A SchiermeyerDepartment of Pathology, The University of Virginia, Charlottesville, VA 22903, USA.
Wei YueDepartment of Pathology, The University of Virginia, Charlottesville, VA 22903, USA.
Robert M CareyDivision of Endocrinology and Metabolism, Department of Medicine, The University of Virginia, Charlottesville, VA 22903, USA.
Pedro A JoseDivision of Renal Diseases & Hypertension, Department of Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC 20052, USA.
Robin A FelderDepartment of Pathology, The University of Virginia, Charlottesville, VA 22903, USA.ORCID 0000-0003-2797-4289
University of Virginia · USGeorge Washington University · US

Funding

Spatiotemporal transregulation of D1-like angiotensin receptors in genetically...P01HL074940 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI JOSE, PEDRO A. · 2004 to 2020
$31.8M
RENAL DOPAMINE-1 RECEPTOR DEFECT IN HYPERTENSIONR01DK039308 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 1987 to 2020
$7.4M
Renal AT2 Receptors in HypertensionR01HL128189 · NHLBI · UNIVERSITY OF VIRGINIA · PI KELLER, SUSANNA R · 2016 to 2024
$5.0M
Lipid rafts, dopamine 1 receptor, and hypertensionR01DK119652 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI JOSE, PEDRO A. · 2020 to 2023
$2.6M
NHLBI NIH HHS P01 HL074940NHLBI NIH HHS R01 HL128189NIDDK NIH HHS DK039308NIDDK NIH HHS DK119652NIDDK NIH HHS R01 DK039308NIDDK NIH HHS R01 DK119652
6 · The paper itself

Abstract

High and low sodium diets are associated with increased blood pressure and cardiovascular morbidity and mortality. The paradoxical response of elevated BP in low salt diets, aka inverse salt sensitivity (ISS), is an understudied vulnerable 11% of the adult population with yet undiscovered etiology. A linear relationship between the number of single nucleotide polymorphisms (SNPs) in the dopamine D

Indexed as

angiotensindopaminedopamine receptorinverse salt sensitivitysalt resistancesaltsensitivity

Identifiers

PMID36359330
PMCPMC9687845
OpenAlexW4308200651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.