Evidence map›Paper›PMID 36359261›Full record

ReviewBiomedicines2022

Antineoplastic Properties by Proapoptotic Mechanisms Induction of

Rossana Migheli, Patrizia Virdis, Grazia Galleri, Caterina Arru, Giada Lostia, Donatella Coradduzza, Maria Rosaria Muroni, Giorgio Pintore, Luigi Podda, Claudio Fozza and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Multi-Target Bioactivity ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Rossana MigheliDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Patrizia VirdisDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Grazia GalleriDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0001-5379-9387
Caterina ArruDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
Giada LostiaDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Donatella CoradduzzaDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
Maria Rosaria MuroniDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Giorgio PintoreDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Luigi PoddaDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Claudio FozzaDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Maria Rosaria De MiglioDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-9393-3234
University of Sassari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a complex disease including approximately 200 different entities that can potentially affect all body tissues. Among the conventional treatments, radiotherapy and chemotherapy are most often applied to different types of cancers. Despite substantial advances in the development of innovative antineoplastic drugs, cancer remains one of the most significant causes of death, worldwide. The principal pitfall of successful cancer treatment is the intrinsic or acquired resistance to therapeutic agents. The development of more effective or synergistic therapeutic approaches to improve patient outcomes and minimize toxicity has become an urgent issue.

Indexed as

cytotoxic effectextrinsic pathway of apoptosisintrinsic pathway of apoptosisInula viscosainuviscolideROS productiontomentosin

Identifiers

PMID36359261
PMCPMC9687476
OpenAlexW4307943152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.