ArticleAnimals : an open access journal from MDPI2022
Genome-Wide Association Studies Revealed Significant QTLs and Candidate Genes Associated with Backfat and Loin Muscle Area in Pigs Using Imputation-Based Whole Genome Sequencing Data.
Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Insulin-like growth factor 2 as a central regulator of growth and metabolic efficiency in livestock: Genetic, nutritional, and biotechnological perspectives.Veterinary world · 2026Review
- Genome-Wide Association Study for Individual Primal Cut Quality Traits in Canadian Commercial Crossbred Pigs.Animals : an open access journal from MDPI · 2025Article
- A genome-wide association study identified candidate regions and genes for commercial traits in a Landrace population.Frontiers in genetics · 2024Article
- Genomic Scan for Runs of Homozygosity and Selective Signature Analysis to Identify Candidate Genes in Large White Pigs.International journal of molecular sciences · 2023Article
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12 authors.
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Abstract
Improvement of carcass features is an essential goal in pig genetic breeding programs. Backfat (BF) and loin muscle area (LMA) are important carcass production metrics and useful indicators of pig production performance and lean meat rate. However, the genetic architecture of BF and LMA traits remains elusive. To identify quantitative trait loci (QTLs) and genes associated with these traits, we performed a genome-wide association study (GWAS) using imputation-based whole genome sequencing data for four phenotypes (adjusted 100 kg BF and LMA, adjusted 100 kg BF EBV and LMA EBV) in 1131 pigs from 3 breeds (French Yorkshire, Landrace, and Duroc). After genotype imputation and quality control, 14,163,315 single nucleotide polymorphisms (SNPs) were retained for further analysis. For the adjusted 100 kg BF trait, using the 2-LOD drop method, a QTL with a 13.4 Kb interval (2.91 to 2.93 Mb on SSC2) and containing a
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