Evidence map›Paper›PMID 36358922›Full record

ReviewBiomolecules2022

Importance of TGFβ in Cancer and Nematode Infection and Their Interaction-Opinion.

Marta Maruszewska-Cheruiyot, Michael James Stear, Maja Machcińska, Katarzyna Donskow-Łysoniewska

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Marta Maruszewska-CheruiyotDepartment of Experimental Immunotherapy, Faculty of Medicine, Lazarski University, 02-662 Warsaw, Poland.ORCID 0000-0002-6595-6228
Michael James StearDepartment of Animal, Plant and Soil Science, Agribio, La Trobe University, Bundoora 3086, Australia.ORCID 0000-0001-5054-1348
Maja MachcińskaDepartment of Experimental Immunotherapy, Faculty of Medicine, Lazarski University, 02-662 Warsaw, Poland.ORCID 0000-0001-5458-0096
Katarzyna Donskow-ŁysoniewskaDepartment of Experimental Immunotherapy, Faculty of Medicine, Lazarski University, 02-662 Warsaw, Poland.ORCID 0000-0003-4924-800X
Uczelnia Łazarskiego · PLLa Trobe University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Historically, there has been little interaction between parasitologists and oncologists, although some helminth infections predispose to the development of tumours. In addition, both parasites and tumours need to survive immune attack. Recent research suggests that both tumours and parasites suppress the immune response to increase their chances of survival. They both co-opt the transforming growth factor beta (TGFβ) signalling pathway to modulate the immune response to their benefit. In particular, there is concern that suppression of the immune response by nematodes and their products could enhance susceptibility to tumours in both natural and artificial infections.

Indexed as

Nematode InfectionsNeoplasmsHumansTransforming Growth Factor betaTransforming Growth Factor betacancerimmunomodulationnematodeTGFβTGFβ mimic

Identifiers

PMID36358922
PMCPMC9687433
OpenAlexW4307552368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.