Evidence map›Paper›PMID 36358773›Full record

ReviewCancers2022

The E3 Ligases in Cervical Cancer and Endometrial Cancer.

Fengguang Zhai, Jie Wang, Weili Yang, Meng Ye, Xiaofeng Jin

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. The SUMOylation and ubiquitination crosstalk in cancer.Journal of cancer research and clinical oncology · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fengguang ZhaiThe Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020, China.
Jie WangThe Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020, China.
Weili YangDepartment of Gynecology, The Affiliated People's Hospital of Ningbo University, Ningbo 315040, China.
Meng YeThe Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020, China.
Xiaofeng JinThe Affiliated Hospital of Medical School, Ningbo University, Ningbo 315020, China.
Ningbo University · CN

Funding

National Natural Science Foundation of China 32270821Natural Science Foundation of Ningbo 2021J065The Fundamental Research Funds for the Provincial Universities of Zhejiang SJLZ2022004The Medical and health science and Technology project of Zhejiang Province 2019337934
6 · The paper itself

Abstract

Endometrial (EC) and cervical (CC) cancers are the most prevalent malignancies of the female reproductive system. There is a global trend towards increasing incidence and mortality, with a decreasing age trend. E3 ligases label substrates with ubiquitin to regulate their activity and stability and are involved in various cellular functions. Studies have confirmed abnormal expression or mutations of E3 ligases in EC and CC, indicating their vital roles in the occurrence and progression of EC and CC. This paper provides an overview of the E3 ligases implicated in EC and CC and discusses their underlying mechanism. In addition, this review provides research advances in the target of ubiquitination processes in EC and CC.

Indexed as

cervical cancerE3 ligaseendometrial carcinomatargeted therapies

Identifiers

PMID36358773
PMCPMC9658772
OpenAlexW4307943836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.