Evidence map›Paper›PMID 36358742›Full record

ArticleCancers2022

The Liver Maximum Capacity Test (LiMAx) Is Associated with Short-Term Survival in Patients with Early Stage HCC Undergoing Transarterial Treatment.

Janett Fischer, Stella Wellhöner, Sebastian Ebel, Thomas Lincke, Albrecht Böhlig, Florian Gerhardt, Rhea Veelken, Holger Goessmann, Karen Geva Steinhoff, Timm Denecke and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Janett FischerDivision of Hepatology, Department of Medicine II, Leipzig University Medical Center, 04103 Leipzig, Germany.ORCID 0000-0002-8710-101X
Stella WellhönerDivision of Hepatology, Department of Medicine II, Leipzig University Medical Center, 04103 Leipzig, Germany.
Sebastian EbelDepartment of Diagnostic and Interventional Radiology, Leipzig University Medical Center, 04103 Leipzig, Germany.
Thomas LinckeDepartment of Nuclear Medicine, Leipzig University Medical Center, 04103 Leipzig, Germany.
Albrecht BöhligDivision of Hepatology, Department of Medicine II, Leipzig University Medical Center, 04103 Leipzig, Germany.
Florian GerhardtDivision of Hepatology, Department of Medicine II, Leipzig University Medical Center, 04103 Leipzig, Germany.
Rhea VeelkenDivision of Hepatology, Department of Medicine II, Leipzig University Medical Center, 04103 Leipzig, Germany.
Holger GoessmannDepartment of Diagnostic and Interventional Radiology, Leipzig University Medical Center, 04103 Leipzig, Germany.
Karen Geva SteinhoffDepartment of Nuclear Medicine, Leipzig University Medical Center, 04103 Leipzig, Germany.ORCID 0000-0002-7598-0758
Timm DeneckeDepartment of Diagnostic and Interventional Radiology, Leipzig University Medical Center, 04103 Leipzig, Germany.ORCID 0000-0003-3313-3208
Osama SabriDepartment of Nuclear Medicine, Leipzig University Medical Center, 04103 Leipzig, Germany.
Thomas BergDivision of Hepatology, Department of Medicine II, Leipzig University Medical Center, 04103 Leipzig, Germany.ORCID 0000-0003-0003-6241
Florian van BömmelDivision of Hepatology, Department of Medicine II, Leipzig University Medical Center, 04103 Leipzig, Germany.ORCID 0000-0003-2679-0672
Leipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transarterial chemoembolization (TACE) and transarterial radioembolization (TARE) are recommended to treat patients with early or intermediate hepatocellular carcinoma (HCC). The liver maximum capacity test (LiMAx) has been supposed to predict the risk of post-interventional liver failure. We investigated the correlation of LiMAx with short-term survival as primary endpoint and the occurrence of adverse events after therapy as secondary endpoint. Our study cohort prospectively included 69 patients receiving TACE (n = 57) or TARE (n = 12). LiMAx test and serological analyses were performed on the day before and 4 weeks after treatment. Hepatic and extrahepatic complications were monitored for 4 weeks. The LiMAx results were not associated with altered liver function and the occurrence of adverse events. The survival rates of patients with BCLC A with LiMAx ≤ 150 μg/kg/h were lower after 30 days (75.0 ± 15.3% vs. 100%,

Indexed as

adverse eventsliver functionsurvivalTACETARE

Identifiers

PMID36358742
PMCPMC9657475
OpenAlexW4308122167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.