Evidence map›Paper›PMID 36358723›Full record

ReviewCancers2022

MicroRNAs' Crucial Role in Salivary Gland Cancers' Onset and Prognosis.

Marco Bocchetti, Piera Grisolia, Federica Melisi, Maria Grazia Ferraro, Pietro De Luca, Angelo Camaioni, Michela Falco, Marianna Abate, Gabriella Misso, Roberto Alfano and 6 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Marco BocchettiDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.ORCID 0000-0002-2143-6669
Piera GrisoliaDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.
Federica MelisiDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.
Maria Grazia FerraroDepartment of Pharmacy, School of Medicine and Surgery, University of Naples "Federico II", Via D. Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-3022-1205
Pietro De LucaDepartment of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, Italy.ORCID 0000-0002-6505-1680
Angelo CamaioniOtolaryngology Department, San Giovanni-Addolorata Hospital, Via dell'Amba Aradam, 8, 00184 Rome, Italy.
Michela FalcoDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.ORCID 0000-0003-4513-8639
Marianna AbateDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.
Gabriella MissoDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.ORCID 0000-0002-7787-2531
Roberto AlfanoDepartment of Advanced Medical and Surgical Sciences "DAMSS", University of Campania "Luigi Vanvitelli", Via S.M. di Costantinopoli 104, 80138 Naples, Italy.
Nunzio AccardoEar Nose Throt Departement AORN Cardarelli, 80100 Napoli, Italy.
Flavia OlivaEar Nose Throt Departement AORN Cardarelli, 80100 Napoli, Italy.
Alessia Maria CossuDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.ORCID 0000-0003-2646-1254
Michele CaragliaDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 7, 80138 Naples, Italy.ORCID 0000-0003-2408-6091
Marianna ScrimaLaboratory of Precision and Molecular Oncology, Biogem Scarl, Institute of Genetic Research, Contrada Camporeale, 83031 Ariano Irpino, Italy.ORCID 0000-0003-4636-7695
Filippo RicciardielloEar Nose Throt Departement AORN Cardarelli, 80100 Napoli, Italy.
University of Campania "Luigi Vanvitelli" · ITOspedale Antonio Cardarelli · ITAzienda Ospedaliera San Giovanni Addolorata · ITBiogem · ITUniversity of Naples Federico II · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salivary gland cancer (SGC) is an uncommon and heterogeneous disease that accounts for around 8.5% of all head and neck cancers. MicroRNAs (miRNAs) consist of a class of highly conserved, short, single-stranded segments (18-25 nucleotides) of noncoding RNA that represent key gene-transcription regulators in physiological and pathological human conditions. However, their role in SGC development and progression is not completely clear. This review aims to compile and summarize the recent findings on the topic, focusing on the prognostic and diagnostic value of the major modulated and validated microRNAs in SGC. Their differential expression could possibly aid the clinician in delivering an early diagnosis, therapeutic strategy and precision medicine.

Indexed as

biomarkersdiagnosismicroRNAsprognosissalivary gland cancer

Identifiers

PMID36358723
PMCPMC9657964
OpenAlexW4307939960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.