Evidence map›Paper›PMID 36358695›Full record

ReviewCancers2022

Integration between Novel Imaging Technologies and Modern Radiotherapy Techniques: How the Eye Drove the Chisel.

Giulio Francolini, Ilaria Morelli, Maria Grazia Carnevale, Roberta Grassi, Valerio Nardone, Mauro Loi, Marianna Valzano, Viola Salvestrini, Lorenzo Livi, Isacco Desideri

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Giulio FrancoliniRadiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, 50134 Florence, Italy.
Ilaria MorelliDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, 50134 Florence, Italy.ORCID 0000-0002-4787-6902
Maria Grazia CarnevaleDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, 50134 Florence, Italy.ORCID 0000-0003-3251-0139
Roberta GrassiDepartment of Precision Medicine, University of Campania "L. Vanvitelli", 80138 Naples, Italy.
Valerio NardoneDepartment of Precision Medicine, University of Campania "L. Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-7347-0965
Mauro LoiRadiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, 50134 Florence, Italy.
Marianna ValzanoDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, 50134 Florence, Italy.
Viola SalvestriniDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, 50134 Florence, Italy.
Lorenzo LiviDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, 50134 Florence, Italy.
Isacco DesideriRadiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, 50134 Florence, Italy.
University of Florence · ITAzienda Ospedaliero-Universitaria Careggi · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTargeted dose-escalation and reduction of dose to adjacent organs at risk have been the main goal of radiotherapy in the last decade. Prostate cancer benefited the most from this process. In recent years, the development of Intensity Modulated Radiation Therapy (IMRT) and Stereotactic Body Radiotherapy (SBRT) radically changed clinical practice, also thanks to the availability of modern imaging techniques. The aim of this paper is to explore the relationship between diagnostic imaging and prostate cancer radiotherapy techniques. MATERIALS AND

methodsAiming to provide an overview of the integration between modern imaging and radiotherapy techniques, we performed a non-systematic search of papers exploring the predictive value of imaging before treatment, the role of radiomics in predicting treatment outcomes, implementation of novel imaging in RT planning and influence of imaging integration on use of RT in current clinical practice. Three independent authors (GF, IM and ID) performed an independent review focusing on these issues. Key references were derived from a PubMed query. Hand searching and clinicaltrials.gov were also used, and grey literature was searched for further papers of interest. The final choice of papers included was discussed between all co-authors.

resultsThis paper contains a narrative report and a critical discussion of the role of new modern techniques in predicting outcomes before treatment, in radiotherapy planning and in the integration with systemic therapy in the management of prostate cancer. Also, the role of radiomics in a tailored treatment approach is explored.

conclusionsIntegration between diagnostic imaging and radiotherapy is of great importance for the modern treatment of prostate cancer. Future clinical trials should be aimed at exploring the real clinical benefit of complex workflows in clinical practice.

Indexed as

multi-parametric magnetic resonance imagingprostate cancerprostate imaging-reporting and data systemsprostate-specific membrane antigen PET/CTradiomics

Identifiers

PMID36358695
PMCPMC9656145
OpenAlexW4307633136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.