ReviewCancers2022
Vulvar Malignant Melanoma: A Narrative Review.
Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 19 citations in OpenAlex.
- Tumor-infiltrating lymphocyte therapy in metastatic vulvar melanoma: A case report and review of the literature.Gynecologic oncology reports · 2026Article
- Concurrent Vulvar and Cutaneous Melanoma in a 40-Year-Old Woman: A Rare Case of Multiple Primary Melanomas.Gynecologic oncology reports · 2026Article
- Under the hood: vulvar anatomy and pathology with a focus on MRI.Abdominal radiology (New York) · 2026Review
- Review
- The potential impact of ACOG guideline changes on genital melanoma detection rates in females: a retrospective cross-sectional analysis and implications for clinical practice.Archives of dermatological research · 2025Article
- Pulsed electric field (PEF) treatment of refractory vulvar melanoma concurrently treated with immune checkpoint blockade demonstrating an abscopal response: A case report.Gynecologic oncology reports · 2025Article
- Pregnancy Complicated by Rapidly Progressing Vulvar Melanoma: A Case Study.The American journal of case reports · 2025Article
- Multidisciplinary Vulvar Cancer Management: The Dermatologist's Perspective.Life (Basel, Switzerland) · 2024Review
- Article
- Vaginal Mucosal Melanoma Cell Activation in Response to Photon or Carbon Ion Irradiation.International journal of particle therapy · 2024Article
- Utilization of immunohistochemistry in gynecologic tumors: An expert review.Gynecologic oncology reports · 2024Review
- Comparison of clinicopathologic features and disease-specific survival in vulvar melanoma versus primary cutaneous sites: a retrospective cohort analysis.Archives of dermatological research · 2024Article
- The prognostic significance of primary tumor site in vulvar cancer: a population-based cohort study.Journal of gynecologic oncology · 2024Article
- Primary vulval melanoma and genital lichen sclerosus.Skin health and disease · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant melanoma is a fatal disease that affects all skin sites. Among these, vulvar melanoma (VM) is a rare gynecological condition that accounts for 5% of all vulvar neoplasms. VM primarily affects older Caucasian women and its relationship to sun exposure is undefined. Diagnosis is defined by biopsy but many clinical, dermatoscopic, and confocal microscopic features can guide doctors. The molecular profile is characterized by the KIT mutation, revealed by all of the technologies that are used (classical sequencing, next-generation sequencing, and immunohistochemical staining). BRAF and NRAS mutations are also common in VM. All of these mutations are possible therapeutic targets. Today, surgery remains the first treatment choice for primary VM. The role of neoadjuvant and adjuvant therapy is scarce and the treatment of relapses is widely debated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.