Evidence map›Paper›PMID 36358556›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Protective Effect of the Hydrophilic Extract of

María Gallego-Rentero, Jimena Nicolás-Morala, Miguel Alonso-Juarranz, Elisa Carrasco, Mikel Portillo-Esnaola, Azahara Rodríguez-Luna, Salvador González

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Changes in ultraviolet B radiation-induced DNA damage and erythema after oral nicotinamide and polypodium leucotomos in healthy volunteers: an intraindividual controlled trial.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  3. The effect of Fernblock® in preventing blue-light-induced oxidative stress and cellular damage in retinal pigment epithelial cells is associated with NRF2 induction.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Article
  4. Clinical Applications ofLife (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

María Gallego-RenteroDepartment of Biology, Faculty of Sciences, Autónoma University of Madrid (UAM), 28049 Madrid, Spain.ORCID 0000-0001-5767-4258
Jimena Nicolás-MoralaDepartment of Biology, Faculty of Sciences, Autónoma University of Madrid (UAM), 28049 Madrid, Spain.
Miguel Alonso-JuarranzOral and Maxillofacial Surgery Service, Hospital Clínico San Carlos, 28040 Madrid, Spain.ORCID 0000-0002-9918-8984
Elisa CarrascoDepartment of Biology, Faculty of Sciences, Autónoma University of Madrid (UAM), 28049 Madrid, Spain.ORCID 0000-0002-0817-1627
Mikel Portillo-EsnaolaDepartment of Biology, Faculty of Sciences, Autónoma University of Madrid (UAM), 28049 Madrid, Spain.
Azahara Rodríguez-LunaDepartment of Basic Health Sciences, Faculty of Health Sciences, Universidad Rey Juan Carlos (URJC), 28933 Alcorcón, Spain.ORCID 0000-0002-1529-7674
Salvador GonzálezDepartment of Medicine and Medical Specialties, Alcalá de Henares University, 28805 Madrid, Spain.ORCID 0000-0001-9282-4784
Instituto Ramón y Cajal de Investigación Sanitaria · ESHospital Clínico San Carlos · ESUniversidad de Alcalá · ESUniversidad Rey Juan Carlos · ES

Funding

Cantabria labs and Instituto de Salud Carlos III and MINECO and FEDER funds (PI18/00708 and PI21) PI18/00708 and PI21
6 · The paper itself

Abstract

Oxidative stress is a harmful effect induced on the skin by polycyclic aromatic hydrocarbons (PAH), including benzo[a]pyrene (BaP) air pollutants. This effect is amplified by the additive damaging effect of the sun, especially through the UVA light component. Besides being one of the main compounds that make up air pollution, BaP can also be found in tar, tobacco smoke, and various foods. In addition to its direct carcinogenic potential, BaP can act as a photosensitizer absorbing sunlight in the UVA range and thus generating ROS and 8-hydroxy-2'-deoxyguanosine (8-OHdG). Fernblock

Indexed as

benzo[a]pyrenekeratinocytesmelanocytesoxidative stressphotopollutionphotoprotectionPolypodium leucotomosultraviolet A radiation

Identifiers

PMID36358556
PMCPMC9686834
OpenAlexW4308443755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.